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The effect of selected pre-analytical phase variables on plasma thromboxane A(2) measurements in humans

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064190%3A_____%2F13%3A%230000472" target="_blank" >RIV/00064190:_____/13:#0000472 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11120/13:43905462

  • Result on the web

    <a href="http://dx.doi.org/10.1111/j.1751-553X.2012.01458.x" target="_blank" >http://dx.doi.org/10.1111/j.1751-553X.2012.01458.x</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1111/j.1751-553X.2012.01458.x" target="_blank" >10.1111/j.1751-553X.2012.01458.x</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    The effect of selected pre-analytical phase variables on plasma thromboxane A(2) measurements in humans

  • Original language description

    Aims: Platelet function testing is often affected by the existence of different pre-analytical variables that can cause platelet activation. The aim of this study was to assess the effect of such variables that are present when samples are taken (different anticoagulants, incubation temperature, and storage conditions) to select those which enable to reach optimal range of measured plasma concentrations of the two stable thromboxane A(2) metabolites, that is, thromboxane B-2 (TxB(2)) and 11-dehydrothromboxane B-2 (11-dTxB(2)). Materials and Methods: For the purpose of this study, whole blood samples obtained from 20 volunteers were screened for TxB(2) and 11-dTxB(2) concentrations using commercial EIA kits (Cayman ChemicalsTM; NeogenTM) in relation tothe effect of different anticoagulants, using different incubation temperatures and storage conditions. Results: Trisodium citrate has been shown not to be affecting the TxB(2) and 11-dTxB(2) concentrations compared with the values measur

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FD - Oncology and haematology

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Others

  • Publication year

    2013

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY

  • ISSN

    1751-5521

  • e-ISSN

  • Volume of the periodical

    35

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    9

  • Pages from-to

    92-100

  • UT code for WoS article

    000316146100018

  • EID of the result in the Scopus database