The effect of selected pre-analytical phase variables on plasma thromboxane A(2) measurements in humans
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064190%3A_____%2F13%3A%230000472" target="_blank" >RIV/00064190:_____/13:#0000472 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11120/13:43905462
Result on the web
<a href="http://dx.doi.org/10.1111/j.1751-553X.2012.01458.x" target="_blank" >http://dx.doi.org/10.1111/j.1751-553X.2012.01458.x</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/j.1751-553X.2012.01458.x" target="_blank" >10.1111/j.1751-553X.2012.01458.x</a>
Alternative languages
Result language
angličtina
Original language name
The effect of selected pre-analytical phase variables on plasma thromboxane A(2) measurements in humans
Original language description
Aims: Platelet function testing is often affected by the existence of different pre-analytical variables that can cause platelet activation. The aim of this study was to assess the effect of such variables that are present when samples are taken (different anticoagulants, incubation temperature, and storage conditions) to select those which enable to reach optimal range of measured plasma concentrations of the two stable thromboxane A(2) metabolites, that is, thromboxane B-2 (TxB(2)) and 11-dehydrothromboxane B-2 (11-dTxB(2)). Materials and Methods: For the purpose of this study, whole blood samples obtained from 20 volunteers were screened for TxB(2) and 11-dTxB(2) concentrations using commercial EIA kits (Cayman ChemicalsTM; NeogenTM) in relation tothe effect of different anticoagulants, using different incubation temperatures and storage conditions. Results: Trisodium citrate has been shown not to be affecting the TxB(2) and 11-dTxB(2) concentrations compared with the values measur
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY
ISSN
1751-5521
e-ISSN
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Volume of the periodical
35
Issue of the periodical within the volume
1
Country of publishing house
US - UNITED STATES
Number of pages
9
Pages from-to
92-100
UT code for WoS article
000316146100018
EID of the result in the Scopus database
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