The Obesity Paradox and Survivors of Ischemic Stroke
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064190%3A_____%2F15%3A%230001053" target="_blank" >RIV/00064190:_____/15:#0001053 - isvavai.cz</a>
Alternative codes found
RIV/00159816:_____/15:00062969 RIV/00216208:11110/15:10295604 RIV/00216208:11140/15:10295604 RIV/00669806:_____/15:10295604 RIV/00023001:_____/15:00059509
Result on the web
<a href="http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2015.03.008" target="_blank" >http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2015.03.008</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2015.03.008" target="_blank" >10.1016/j.jstrokecerebrovasdis.2015.03.008</a>
Alternative languages
Result language
angličtina
Original language name
The Obesity Paradox and Survivors of Ischemic Stroke
Original language description
Background: Although obesity is a risk factor for stroke and achieving normal weight is advocated to decrease stroke risk, the risk associated with obesity and weight loss after stroke has not been well established. The aim of this study was to assess the association of obesity at the time of stroke admission and weight loss after stroke with total mortality. Methods: We analyzed 736 consecutive patients (mean age, 66 6 11 years; 58% men) hospitalized for their first ischemic stroke. Body weight at hospital admission and at the outpatient visit during follow-up was used in the analysis. Results: After multivariate adjustment, obesity at admission was associated with lower mortality risk as compared with normal weight (hazard ratio [HR],.50, P = .03). At the outpatient visit, with a median follow-up time of 16 months, 21% of patients had lost more than 3 kg of weight. Stroke severity, heart failure, transient ischemic attack, and depression after stroke were independently associated with significant weight loss. Weight loss of more than 3 kg was associated with increased mortality risk (HR, 5.87; P = .001) independently of other factors. Similar results were seen when weight loss was defined as losing more than 3% of baseline weight (HR, 4.97; P = .004). Weight gain of more than 5% of the baseline weight tended to be associated with better survival when compared with no weight change (log-rank test, P = .07). Conclusions: Normal weight at hospital admission and weight loss after ischemic stroke are independently associated with increased mortality. Overweight and obesity at baseline do not decrease the risk associated with weight loss.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FA - Cardiovascular diseases including cardio-surgery
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
ISSN
1052-3057
e-ISSN
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Volume of the periodical
24
Issue of the periodical within the volume
6
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
8
Pages from-to
1443-1450
UT code for WoS article
000355338200060
EID of the result in the Scopus database
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