The DRD2/ANKK1 Taq1A polymorphism is associated with smoking cessation failure in patients with coronary heart disease
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064190%3A_____%2F15%3A%230001075" target="_blank" >RIV/00064190:_____/15:#0001075 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/15:10312510 RIV/00216208:11140/15:10312510 RIV/00669806:_____/15:10312510 RIV/00159816:_____/15:00068448
Result on the web
<a href="http://dx.doi.org/10.2217/pme.15.16" target="_blank" >http://dx.doi.org/10.2217/pme.15.16</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2217/pme.15.16" target="_blank" >10.2217/pme.15.16</a>
Alternative languages
Result language
angličtina
Original language name
The DRD2/ANKK1 Taq1A polymorphism is associated with smoking cessation failure in patients with coronary heart disease
Original language description
Aim: We speculated whether DRD2 or CHRN subunit polymorphisms might be associated with the risk of smoking cessation failure in subjects after coronary heart disease (CHD) manifestation. Methods: A total of 964 patients with CHD, mean age 64.3 years (standard deviation [SD]9.0), examined in the EUROASPIRE III and IV surveys were genotyped for rs1800497 (DRD2/-ANKK1 Taq1A), rs578776 (CHRNA5-A3-B4), rs16969968 (CHRNA5) and rs1051730 (CHRNA3) SNPs. Results: The presence of DRD2/-ANKK1 Taq1A minor T allele was independently associated with increased relative risk of smoking persistence (odds ratio: 1.79; 95% CI: 1.13-4.35). We observed no association between CHRN SNPs and smoking habit. Conclusion: DRD2/-ANKK1 Taq1A polymorphism is associated with a decreased likelihood of smoking cessation in patients after CHD manifestation.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FA - Cardiovascular diseases including cardio-surgery
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
PERSONALIZED MEDICINE
ISSN
1741-0541
e-ISSN
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Volume of the periodical
12
Issue of the periodical within the volume
5
Country of publishing house
GB - UNITED KINGDOM
Number of pages
11
Pages from-to
463-473
UT code for WoS article
000362897700006
EID of the result in the Scopus database
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