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Endothelial cell-derived microvesicles: potential mediators and biomarkers of pathologic processes

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064190%3A_____%2F18%3AN0000034" target="_blank" >RIV/00064190:_____/18:N0000034 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11110/18:10376408

  • Result on the web

    <a href="http://dx.doi.org/10.2217/bmm-2017-0182" target="_blank" >http://dx.doi.org/10.2217/bmm-2017-0182</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.2217/bmm-2017-0182" target="_blank" >10.2217/bmm-2017-0182</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Endothelial cell-derived microvesicles: potential mediators and biomarkers of pathologic processes

  • Original language description

    This review focuses on the formation, composition and function of endothelial microvesicles (MV), often called microparticles (MP). MV release is a controlled event and is considered a hallmark of cellular activation or alteration. MV may affect the function of target cells through surface interaction and receptor activation, cellular fusion and the delivery of intravesicular cargo. Endothelial MV are released as a consequence of endothelial activation during inflammation and have been described to affect hemostasis, various aspects of inflammatory reaction, vessel formation, apoptosis and cell survival, endothelial cell differentiation and function. Recent data suggest the potential use of MV in diagnostics, assessment of severity and prediction of outcomes in inflammatory diseases and their utilization as targets, mediators and vectors in therapy.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30230 - Other clinical medicine subjects

Result continuities

  • Project

    <a href="/en/project/NV16-27800A" target="_blank" >NV16-27800A: Endothelial injury in newborns: diagnostic significance of biomarkers and microparticles in diseases influencing neonatal mortality and morbidity</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2018

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    BIOMARKERS IN MEDICINE

  • ISSN

    1752-0363

  • e-ISSN

    1752-0371

  • Volume of the periodical

    12

  • Issue of the periodical within the volume

    2

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    15

  • Pages from-to

    161-175

  • UT code for WoS article

    000424013300009

  • EID of the result in the Scopus database

    2-s2.0-85041425236