Intravenous administration of normal saline may be misinterpreted as a change of end-expiratory lung volume when using electrical impedance tomography
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064190%3A_____%2F19%3AN0000061" target="_blank" >RIV/00064190:_____/19:N0000061 - isvavai.cz</a>
Alternative codes found
RIV/68407700:21460/19:00331793 RIV/00216208:11110/19:10397512
Result on the web
<a href="http://dx.doi.org/10.1038/s41598-019-42241-7" target="_blank" >http://dx.doi.org/10.1038/s41598-019-42241-7</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1038/s41598-019-42241-7" target="_blank" >10.1038/s41598-019-42241-7</a>
Alternative languages
Result language
angličtina
Original language name
Intravenous administration of normal saline may be misinterpreted as a change of end-expiratory lung volume when using electrical impedance tomography
Original language description
Electrical impedance tomography (EIT) is a noninvasive imaging modality that allows real-time monitoring of regional lung ventilation. The aim of the study is to investigate whether fast saline infusion causes changes in lung impedance that could affect the interpretation of EIT data. Eleven pigs were anaesthetized and mechanically ventilated. A bolus of 500 mL of normal saline was administered rapidly. Two PEEP steps were performed to allow quantification of the effect of normal saline on lung impedance. The mean change of end-expiratory lung impedance (EELI) caused by the saline bolus was equivalent to a virtual decrease of end-expiratory lung volume (EELV) by 227 (188-250) mL and decremental PEEP step of 4.40 (3.95-4.59) cm H2O (median and interquartile range). In contrast to the changes of PEEP, the administration of normal saline did not cause any significant differences in measured EELV, regional distribution of lung ventilation determined by EIT or in extravascular lung water and intrathoracic blood volume. In conclusion, EELI can be affected by the changes of EELV as well as by the administration of normal saline. These two phenomena can be distinguished by analysis of regional distribution of lung ventilation.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30224 - Radiology, nuclear medicine and medical imaging
Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
SCIENTIFIC REPORTS
ISSN
2045-2322
e-ISSN
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Volume of the periodical
9
Issue of the periodical within the volume
04/2019
Country of publishing house
GB - UNITED KINGDOM
Number of pages
8
Pages from-to
Article Number: 5775
UT code for WoS article
000463695800028
EID of the result in the Scopus database
2-s2.0-85064093434