Comparison of end-expiratory lung volume measurement by electrical impedance tomography and nitrogen washout method in pigs

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F20%3A00352408" target="_blank" >RIV/68407700:21460/20:00352408 - isvavai.cz</a>

Result on the web

<a href="https://doi.org/10.14311/CTJ.2020.4.05" target="_blank" >https://doi.org/10.14311/CTJ.2020.4.05</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.14311/CTJ.2020.4.05" target="_blank" >10.14311/CTJ.2020.4.05</a>

Result language

angličtina

Original language name

Comparison of end-expiratory lung volume measurement by electrical impedance tomography and nitrogen washout method in pigs

Original language description

End-expiratory lung volume (EELV) can be determined using several methods. Electrical impedance tomography (EIT) is offered as another method for measuring EELV. The aim of the study is to compare changes in EELV measured by nitrogen washout method with changes of EELV calculated from the change in end-expiratory lung impedance (EELI) measured by EIT and to determine whether changes in EELV calculated from changes in chest impedance can be used as one of the parameters for EIT data analysis and description. The prospective interventional animal study was performed on ten pigs. 16-electrode EIT system was used for data acquisition. The study protocol consisted of the baseline phase, two incremental PEEP steps, two decremental PEEP steps and from normal saline i. v. administration. For each breath cycle, tidal variation image was calculated as a difference between the end-inspiratory and the previous end-expiratory EIT image. An equivalent end-expiratory volume change (ΔEELVequiv) was calculated from EELI. The values of ΔEELVequiv were compared with reference EELV data measured by a modified nitrogen wash-in/wash-out technique (ΔEELVmeas). The measured and the estimated changes in EELV were statistically compared and correlation between ΔEELVequiv and ΔEELVmeas was calculated. Statistically significant difference between ΔEELVequiv and ΔEELVmeas was observed only in administration of normal saline bolus. Pearson’s correlation coefficients were 0.29 for increase in PEEP, 0.45 for decrease in PEEP and -0.1 during administration of normal saline bolus. The study showed that during changes in PEEP in the porcine model, there was no linear relationship between ΔEELVequiv and ΔEELVmeas. Although there was no linear relationship between ΔEELVequiv and ΔEELVmeas with changes in PEEP, no statistically significant difference was demonstrated between these two methods, which justifies the use of ΔEELVequiv as a parameter suitable for description and evaluation of EIT data.

Czech name

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Czech description

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Type

J_SC - Article in a specialist periodical, which is included in the SCOPUS database

CEP classification

—

OECD FORD branch

20601 - Medical engineering

Project

—

Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2020

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Lékař a technika

ISSN

0301-5491

e-ISSN

—

Volume of the periodical

50

Issue of the periodical within the volume

4

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

6

Pages from-to

146-151

UT code for WoS article

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EID of the result in the Scopus database

2-s2.0-85117243516