Prevalence and mortality in children with congenital diaphragmatic hernia: a multicountry study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064190%3A_____%2F20%3AN0000120" target="_blank" >RIV/00064190:_____/20:N0000120 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1016/j.annepidem.2020.11.007" target="_blank" >http://dx.doi.org/10.1016/j.annepidem.2020.11.007</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.annepidem.2020.11.007" target="_blank" >10.1016/j.annepidem.2020.11.007</a>

Result language

angličtina

Original language name

Prevalence and mortality in children with congenital diaphragmatic hernia: a multicountry study

Original language description

Purpose: This study determined the prevalence, mortality, and time trends of children with congenital diaphragmatic hernia (CDH). Methods: Twenty-five hospital- and population-based surveillance programs in 19 International Clearinghouse for Birth Defects Surveillance and Research member countries provided birth defects mortality data between 1974 and 2015. CDH cases included live births, stillbirths, or elective termination of pregnancy for fetal anomalies. Prevalence, cumulative mortality rates, and 95% confidence intervals (CIs) were calculated using Poisson regression and a Kaplan–Meier product-limit method. Joinpoint regression analyses were conducted to assess time trends. Results: The prevalence of CDH was 2.6 per 10,000 total births (95% CI: 2.5–2.7), slightly increasing between 2001 and 2012 (average annual percent change = 0.5%; 95% CI:−0.6 to 1.6). The total percent mortality of CDH was 37.7%, with hospital-based registries having more deaths among live births than population-based registries (45.1% vs. 33.8%). Mortality rates decreased over time (average annual percent change = −2.4%; 95% CI: −3.8 to 1.1). Most deaths due to CDH occurred among 2- to 6-day-old infants for both registry types (36.3%, hospital-based; 12.1%, population-based). Conclusions: The mortality of CDH has decreased over time. Mortality remains high during the first week and varied by registry type.

Czech name

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Czech description

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Type

J_SC - Article in a specialist periodical, which is included in the SCOPUS database

CEP classification

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OECD FORD branch

30101 - Human genetics

Project

<a href="/en/project/NV17-29622A" target="_blank" >NV17-29622A: Effectiveness analysis of prenatal diagnosis of congenital malformations and survival of children born with a birth defect in 1994 – 2015</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2020

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Annals of Epidemiology

ISSN

1047-2797

e-ISSN

1873-2585

Volume of the periodical

56

Issue of the periodical within the volume

April 2021

Country of publishing house

US - UNITED STATES

Number of pages

9

Pages from-to

61-69

UT code for WoS article

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EID of the result in the Scopus database

2-s2.0-85098163350