Prevalence and mortality among children with anorectal malformation: A multi-country analysis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064190%3A_____%2F23%3A10000997" target="_blank" >RIV/00064190:_____/23:10000997 - isvavai.cz</a>
Alternative codes found
RIV/00064190:_____/22:N0000060
Result on the web
<a href="https://doi.org/10.1002/bdr2.2129" target="_blank" >https://doi.org/10.1002/bdr2.2129</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/bdr2.2129" target="_blank" >10.1002/bdr2.2129</a>
Alternative languages
Result language
angličtina
Original language name
Prevalence and mortality among children with anorectal malformation: A multi-country analysis
Original language description
Purpose: We examined the total prevalence, trends in prevalence, and age-specific mortality among individuals with anorectal malformation (ARM). Methods: We conducted a retrospective cohort study using data from 24 population- and hospital-based birth defects surveillance programs affiliated with the International Clearinghouse for Birth Defects Surveillance and Research (ICBDSR) from 18 countries and for births from 1974 to 2014. We estimated pooled and program-specific total prevalence per 10,000 total births. Poisson regression was used to assess time trends in prevalence from 2001 to 2012 when most programs contributed data. We calculated selected age-specific proportions of deaths, stratified by case status. Results: The pooled total prevalence of ARM was 3.26 per 10,000 total births (95% Confidence Interval = 3.19, 3.32) for birth years 1974-2014. About 60% of cases were multiple or syndromic. Prevalence of multiple, syndromic, and stillborn cases decreased from 2001 to 2012. The first week mortality proportion was 12.5%, 3.2%, 28.3%, and 18.2% among all, isolated, multiple, and syndromic cases, respectively. Conclusions: ARM is relatively rare, with multiple and syndromic cases showing decreasing prevalence during the study period. Mortality is a concern during the first week of life, and especially among multiple and syndromic cases. Our descriptive epidemiological findings increase our understanding of geographic variation in the prevalence of ARM and can be used to plan needed clinical services. Exploring factors influencing prevalence and mortality among individuals with ARM could inform future studies. (C) 2022 The Authors. Birth Defects Research published by Wiley Periodicals LLC.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10605 - Developmental biology
Result continuities
Project
—
Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
BIRTH DEFECTS RESEARCH
ISSN
2472-1727
e-ISSN
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Volume of the periodical
115
Issue of the periodical within the volume
3
Country of publishing house
US - UNITED STATES
Number of pages
15
Pages from-to
390-404
UT code for WoS article
000898736100001
EID of the result in the Scopus database
2-s2.0-85142275133