Discard volume necessary for elimination of heparin flush effect on thromboelastography

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F10%3A6060" target="_blank" >RIV/00064203:_____/10:6060 - isvavai.cz</a>

Alternative codes found

RIV/60460709:41110/10:47958 RIV/00216208:11130/10:6060

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Discard volume necessary for elimination of heparin flush effect on thromboelastography

Original language description

Heparin is used to prevent obstruction of indwelling arterial catheters with blood clots. It is known to affect the outcomes of analysis of coagulation parameters with thromboelastography (TEG). The aim of this study was to evaluate the minimal discard blood volume needed to eliminate the effect of heparin flush on TEG. Ten patients were included in the study. Coagulation parameters were evaluated with kaolin-activated TEG. Blood samples were obtained after discarding 1, 2, 3, 4, 5 or 10 ml of blood toeliminate the effect of heparin. We found an increase in coagulation (reflecting the heparin elimination) with the increasing discard volume between 1 and 4 ml. This was obvious from an increase in alpha angle and maximal amplitude of the measured clot and a decrease in R and time to maximal amplitude of the measured clot (P<0.001). However, values obtained after discarding 4, 5 and 10 ml of blood did not differ markedly. To obtain valid information, it is necessary to discard volume of

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FJ - Surgery including transplantology

OECD FORD branch

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Project

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Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Blood Coagulation & Fibrinolysis

ISSN

0957-5235

e-ISSN

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Volume of the periodical

21

Issue of the periodical within the volume

2

Country of publishing house

GB - UNITED KINGDOM

Number of pages

4

Pages from-to

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UT code for WoS article

000274513600017

EID of the result in the Scopus database

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