Opposing and synergistic effects of cyclic mechanical stretch and alpha- or beta-adrenergic stimulation on the cardiac gap junction protein Cx43
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F10%3A6675" target="_blank" >RIV/00064203:_____/10:6675 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Opposing and synergistic effects of cyclic mechanical stretch and alpha- or beta-adrenergic stimulation on the cardiac gap junction protein Cx43
Original language description
In the heart the most prominant cardiac gap junction protein is connexin43 (Cx43). Increased Cx43 expression has been indentified in cardiac hypertrophy and may contribute to arrhythmias. Gap junction channels form the basis for direct intercellular communication and are important for a regular function of all organs. It has been shawn by several working groups that beta- and alpha-adrenoreceptors might participate in hypertrophic responses and by our working group that beta- or alfa-adrenoreceptor stimulation alters Cx43 expression.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
ED - Physiology
OECD FORD branch
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Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Pharmacological Research
ISSN
1043-6618
e-ISSN
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Volume of the periodical
62
Issue of the periodical within the volume
6
Country of publishing house
GB - UNITED KINGDOM
Number of pages
8
Pages from-to
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UT code for WoS article
000284965700006
EID of the result in the Scopus database
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