The Use of Oligoperoxide-Coated Magnetic Nanoparticles to Label Stem Cells
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F11%3A7054" target="_blank" >RIV/00064203:_____/11:7054 - isvavai.cz</a>
Alternative codes found
RIV/68378041:_____/11:00363241 RIV/61389013:_____/11:00363241 RIV/00023001:_____/11:00002744 RIV/00216208:11130/11:7054
Result on the web
<a href="http://www.ncbi.nlm.nih.gov/pubmed/21830479" target="_blank" >http://www.ncbi.nlm.nih.gov/pubmed/21830479</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
The Use of Oligoperoxide-Coated Magnetic Nanoparticles to Label Stem Cells
Original language description
Iron oxide nanoparticles obtained by the coprecipitation of Fe(II) and Fe(III) salts and oxidation were coated with a novel poly(vinyl acetate-co-5-tert-(butylperoxy)-5-methylhex-1-en-3-yne-co-butyl acrylate-co-maleic anhydride) (PVBM) oligomer to ensurecolloidal stability. The magnetic nanoparticles were thoroughly characterized by a range of physico-chemical methods, which proved the presence of the coating on the particles. Experiments with rat mesenchymal stem cells (rMSCs) confirmed that PVBM-coated gamma-Fe2O3 nanoparticles were not cytotoxic and that the average efficiency of stem cell labeling was good and comparable to that obtained with commercial agents. The cells labeled with PVBM-coated gamma-Fe2O3 nanoparticles displayed excellent contrast on magnetic resonance (MR) images. Such particles are thus promising for in vivo MR imaging of transplanted cells. Moreover, PVBM offers the possibility of additional modification by grafting compounds that reduce non-specific protein
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FP - Other medical fields
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Biomedical Nanotechnology
ISSN
1550-7033
e-ISSN
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Volume of the periodical
7
Issue of the periodical within the volume
3
Country of publishing house
US - UNITED STATES
Number of pages
11
Pages from-to
384-394
UT code for WoS article
000292858900008
EID of the result in the Scopus database
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