Immunolocalization of protein-bound 3-nitrotyrosine in inflammatory myopathies
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F11%3A7242" target="_blank" >RIV/00064203:_____/11:7242 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11130/11:7242 RIV/00023728:_____/11:#0001017
Result on the web
<a href="http://www.cspatologie.cz/docs/369-abstraktCZ.pdf" target="_blank" >http://www.cspatologie.cz/docs/369-abstraktCZ.pdf</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Immunolocalization of protein-bound 3-nitrotyrosine in inflammatory myopathies
Original language description
3-nitrotyrosine (3NT) is regarded as a ?footprint? of nitric oxide generation. The study aimed at documenting the presence and distribution of 3-nitrotyrosine (3NT) in muscle tissue samples from patients with idiopathic inflammatory myopathies (IIM) as well as from those with non-inflammatory myopathies to consider whether polymyositis (PM) and dermatomyositis (DM) could be distinguished based on 3NT immunohistochemistry in muscle biopsy. Cryosections prepared from muscle biopsies of 54 patients with either IIM, i.e. PM and DM, or various non-inflammatory myopathies were immunostained using monoclonal antibody against 3NT. The 3NT immunostaining was localized to endothelial cells and their close surroundings in muscle biopsies of DM and PM patients butonly in those areas of tissue sections where inflammatory cell infiltrates were present. No 3NT positivity was found in tissue sections of IIM patients without inflammatory infiltrates in the studied sample as well as in muscle tissue se
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EC - Immunology
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Česko-slovenská patologie a soudní lékařství
ISSN
1210-7875
e-ISSN
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Volume of the periodical
47-56
Issue of the periodical within the volume
2
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
4
Pages from-to
62-65
UT code for WoS article
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EID of the result in the Scopus database
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