The association between left ventricular diastolic function and a mild-to-moderate decrease in glomerular filtration rate in patients with type 2 diabetes mellitus

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F11%3A7262" target="_blank" >RIV/00064203:_____/11:7262 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11130/11:7262 RIV/00023761:_____/11:#0000336
Result on the web
<a href="http://www.ncbi.nlm.nih.gov/pubmed/22289533" target="_blank" >http://www.ncbi.nlm.nih.gov/pubmed/22289533</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
The association between left ventricular diastolic function and a mild-to-moderate decrease in glomerular filtration rate in patients with type 2 diabetes mellitus
Original language description
This prospective study evaluated the relationship between echocardiography parameters of left ventricular (LV) diastolic function and mild-to-moderate renal function impairment in 82 patients with type 2 diabetes mellitus. The mean age of the patients was 61.1 years. A significant correlation was found between estimated glomerular filtration rate (eGFR) and the ratio of peak velocity of early transmitral flow (E) to peak velocity of early diastolic mitral annular motion (E). Cluster analysis revealed two subgroups of patients with different E values but comparable eGFRs. The correlation between eGFR and E/E was significant in 38 patients with E 7.1 cm/s, but not significant in 44 patients with E > 7.1 cm/s. The results suggest that the deterioration ofLV relaxation (E) represents the underlying condition for the association between mild-to-moderate renal function impairment and the noninvasive parameter of LV end-diastolic pressure (E/E), in patients with type 2 diabetes without any p
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FB - Endocrinology, diabetology, metabolism, nutrition
OECD FORD branch
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Project
<a href="/en/project/NR9520" target="_blank" >NR9520: Diastolic dysfunction in diabetes mellitus II.type. The significance of the selected clinical, metabolic and endocrine parameters</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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