Persistence of humoral immunity to tetanus and diphtheria in hematopoietic stem cell transplant recipients after post-transplant immunization
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F12%3A8111" target="_blank" >RIV/00064203:_____/12:8111 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1002/pbc.24186" target="_blank" >http://dx.doi.org/10.1002/pbc.24186</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Persistence of humoral immunity to tetanus and diphtheria in hematopoietic stem cell transplant recipients after post-transplant immunization
Original language description
Background Persistence of humoral immunity was evaluated in 82 hematopoietic stem cell transplant recipients up to 12.5 years after post-transplant immunization against tetanus and diphtheria. Procedure New immunization, initiated at least 12 months after transplantation, consisted of an average three-dose schedule of vaccine administration on day 1, month 3, and month 12. Serological data were collected at pre-transplant, post-transplant, vaccination, and post-vaccination time points. Results The firstvaccination dose elicited a seroprotective response in most recipients, but the complete vaccine series (usually three-dose schedule) reinforced the specific immunity in most vaccinated cases, that is, 100% and 95.8% seroprotection against tetanus and diphtheria, respectively. Geometric mean concentration post-vaccination tetanus and diphtheria antibody levels persisted at 1.9?IU (95% CI: 1.232.94?IU/ml) and 0.20?IU (95% CI: 0.110.38?IU/ml) for 7 years, respectively. However, diphtheria
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Pediatric Blood & Cancer
ISSN
1545-5009
e-ISSN
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Volume of the periodical
59
Issue of the periodical within the volume
5
Country of publishing house
US - UNITED STATES
Number of pages
6
Pages from-to
908-913
UT code for WoS article
000308656100025
EID of the result in the Scopus database
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