Repeated Multilevel Botulinum Toxin A Treatment Maintains Long-Term Walking Ability in Children with Cerebral Palsy

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F12%3A8142" target="_blank" >RIV/00064203:_____/12:8142 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11130/12:8142
Result on the web
<a href="http://www.csnn.eu/ceska-slovenska-neurologie-clanek/opakovana-viceetazova-aplikace-botulinum-toxinu-a-dlouhodobe-zabranuje-zhorseni-chuze-u-deti-s-detskou-mozkovou-obrnou-38959" target="_blank" >http://www.csnn.eu/ceska-slovenska-neurologie-clanek/opakovana-viceetazova-aplikace-botulinum-toxinu-a-dlouhodobe-zabranuje-zhorseni-chuze-u-deti-s-detskou-mozkovou-obrnou-38959</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Repeated Multilevel Botulinum Toxin A Treatment Maintains Long-Term Walking Ability in Children with Cerebral Palsy
Original language description
Aims: Botulinum toxin type A (BoNT-A) offers a targeted form of therapy to reduce spasticity and has become a standard form of treatment in children with cerebral palsy (CP). However, the effects of repeated BoNT-A treatment over a longer periods of timeare not well known. We hypothesized that children treated with multi-level, high-dose, repeated BoNT-A applications would not deteriorate in their gait function over a minimum period of four years. Materials and methodology: Gait in 18 children with spastic diplegic CP, mean age 6 years 9 months, Gross Motor Function Classification System I-III, treated according to the concept of integrated BoNT-A application over a minimum of four years was evaluated using the kinematic and kinetic gait analysis. Themain outcome measure was the Gait Deviation Index (GDI). Results: The mean follow-up time was 5 years and 9 months (SD 1 year 5 months). Each child received a mean of 1.02 (SD 0.37) applications of BoNT-A per year. The gait function asse
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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