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Regulatory T cells, dendritic cells and neutrophils in patients with renal cell carcinoma

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F13%3A10209750" target="_blank" >RIV/00064203:_____/13:10209750 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11130/13:10209750

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.imlet.2013.05.010" target="_blank" >http://dx.doi.org/10.1016/j.imlet.2013.05.010</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.imlet.2013.05.010" target="_blank" >10.1016/j.imlet.2013.05.010</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Regulatory T cells, dendritic cells and neutrophils in patients with renal cell carcinoma

  • Original language description

    We evaluated dendritic cells (DC), regulatory T lymphocytes (Treg) and neutrophils in 37 patients with newly diagnosed renal cell carcinoma (RCC) in the tumor and peripheral blood (PB) and correlated these parameters with tumor staging (early-T1, 2, late-T3, 4 and metastatic disease). The number of myeloid and plasmacytoid DC in blood of RCC patients was higher than in healthy controls. The percentage of myeloid dendritic cells (mDC) from CD45+ cells in tumors was higher in comparison with peripheral blood irrespective of disease stage. Higher percentage of these cells expressed a maturation marker in the periphery in the early stage (CD83 expressing cells). The number of plasmacytoid dendritic cells (pDC) in PB was similar in both early and late stagegroups, but the early group displayed a significantly higher percentage of pDC in tumor cell suspension. Neutrophil counts in the peripheral blood of RCC patients were higher than in healthy controls, but the counts in-both tumor stage g

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EC - Immunology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/NT11559" target="_blank" >NT11559: Dendritic cell based cancer immunotherapy of prostate cancer Phase I/II clinical trial</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2013

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Immunology Letters

  • ISSN

    0165-2478

  • e-ISSN

  • Volume of the periodical

    152

  • Issue of the periodical within the volume

    2

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    7

  • Pages from-to

    144-150

  • UT code for WoS article

    000322294100010

  • EID of the result in the Scopus database