Distinctive MRI features of the epileptogenic zone in children with tuberous sclerosis

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F14%3A10292758" target="_blank" >RIV/00064203:_____/14:10292758 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11130/14:10292758 RIV/68407700:21230/14:00223669

Result on the web

<a href="http://dx.doi.org/10.1016/j.ejrad.2013.12.024" target="_blank" >http://dx.doi.org/10.1016/j.ejrad.2013.12.024</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ejrad.2013.12.024" target="_blank" >10.1016/j.ejrad.2013.12.024</a>

Result language

angličtina

Original language name

Distinctive MRI features of the epileptogenic zone in children with tuberous sclerosis

Original language description

Objective: Localization of the epileptogenic zone (EZ) is challenging in children with tuberous sclerosis complex (TSC). We sought to ascertain whether brain MRI could identify the EZ in TSC patients independent of the clinical and diagnostic data. Methods: Presurgical MRI's of 34 children with TSC who underwent epilepsy surgery at Miami Children's Hospital were retrospectively reevaluated by experts blinded to all other data. Changes typical of TSC (tubers, calcifications, cystic changes) and abnormalities of the perituberal cortex typical of focal cortical dysplasia (FCD) (increased cortical thickness, abnormal gyration, transmantle change, gray/white matter junction blurring) were identified and their localization was compared with the resection site. Sensitivity, specificity and accuracy of individual MRI features to localize the EZ were determined and statistically compared between postoperatively seizure-free and non-seizure-free patients as well as clusters of features typical o

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

European Journal of Radiology

ISSN

0720-048X

e-ISSN

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Volume of the periodical

83

Issue of the periodical within the volume

4

Country of publishing house

IE - IRELAND

Number of pages

7

Pages from-to

703-709

UT code for WoS article

000332405200016

EID of the result in the Scopus database

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