Consensus guidelines for the detection of immunogenic cell death
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F14%3A10293140" target="_blank" >RIV/00064203:_____/14:10293140 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11130/14:10293140
Result on the web
<a href="http://dx.doi.org/10.4161/21624011.2014.955691" target="_blank" >http://dx.doi.org/10.4161/21624011.2014.955691</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.4161/21624011.2014.955691" target="_blank" >10.4161/21624011.2014.955691</a>
Alternative languages
Result language
angličtina
Original language name
Consensus guidelines for the detection of immunogenic cell death
Original language description
Apoptotic cells have long been considered as intrinsically tolerogenic or unable to elicit immune responses specific for dead cell-associated antigens. However, multiple stimuli can trigger a functionally peculiar type of apoptotic demise that does not go unnoticed by the adaptive arm of the immune system, which we named "immunogenic cell death" (ICD). ICD is preceded or accompanied by the emission of a series of immunostimulatory damage-associated molecular patterns (DAMPs) in a precise spatiotemporalconfiguration. Several anticancer agents that have been successfully employed in the clinic for decades, including various chemotherapeutics and radiotherapy, can elicit ICD. Moreover, defects in the components that underlie the capacity of the immune system to perceive cell death as immunogenic negatively influence disease outcome among cancer patients treated with ICD inducers. Thus, ICD has profound clinical and therapeutic implications. Unfortunately, the gold-standard approach to de
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EC - Immunology
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
OncoImmunology
ISSN
2162-4011
e-ISSN
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Volume of the periodical
3
Issue of the periodical within the volume
9
Country of publishing house
US - UNITED STATES
Number of pages
19
Pages from-to
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UT code for WoS article
000346922400019
EID of the result in the Scopus database
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