Atypical language representation in children with intractable temporal lobe epilepsy

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F16%3A10324093" target="_blank" >RIV/00064203:_____/16:10324093 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11130/16:10324093 RIV/00216208:11210/16:10324093 RIV/00843989:_____/16:E0105397 RIV/61988987:17110/16:A21026XW

Result on the web

<a href="http://dx.doi.org/10.1016/j.yebeh.2016.03.006" target="_blank" >http://dx.doi.org/10.1016/j.yebeh.2016.03.006</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.yebeh.2016.03.006" target="_blank" >10.1016/j.yebeh.2016.03.006</a>

Result language

angličtina

Original language name

Atypical language representation in children with intractable temporal lobe epilepsy

Original language description

This study evaluated language organization in children with intractable epilepsy caused by temporal lobe focal cortical dysplasia (FCD) alone or dual pathology (temporal lobe FCD and hippocampal sclerosis, HS). We analyzed clinical, neurological, fMRI, neuropsychological, and histopathologic data in 46 pediatric patients with temporal lobe lesions who underwent excisional epilepsy surgery. The frequency of atypical language representation was similar in both groups, but children with dual pathology were more likely to be left-handed. Atypical receptive language cortex correlated with lower intellectual capacity, verbal abstract conceptualization, receptive language abilities, verbal working memory, and a history of status epilepticus but did not correlate with higher seizure frequency or early seizure onset. Histopathologic substrate had only a minor influence on neuropsychological status. Greater verbal comprehension deficits were noted in children with atypical receptive language representation, a risk factor for cognitive morbidity.

Czech name

—

Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

—

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Epilepsy &amp; Behavior

ISSN

1525-5050

e-ISSN

—

Volume of the periodical

58

Issue of the periodical within the volume

May

Country of publishing house

US - UNITED STATES

Number of pages

6

Pages from-to

91-96

UT code for WoS article

000376455100016

EID of the result in the Scopus database

2-s2.0-84962743626