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Atypical language representation in children with intractable temporal lobe epilepsy

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F16%3AA21026XW" target="_blank" >RIV/61988987:17110/16:A21026XW - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11130/16:10324093 RIV/00216208:11210/16:10324093 RIV/00843989:_____/16:E0105397 RIV/00064203:_____/16:10324093

  • Result on the web

    <a href="https://reader.elsevier.com/reader/sd/pii/S1525505016001220?token=55D755C4EB8606A48B9D6CFDF03C95E843236F750E89F0DD1E5BCA7068EB8EC242744988AAADA7B1A33AB4B41D280415" target="_blank" >https://reader.elsevier.com/reader/sd/pii/S1525505016001220?token=55D755C4EB8606A48B9D6CFDF03C95E843236F750E89F0DD1E5BCA7068EB8EC242744988AAADA7B1A33AB4B41D280415</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.yebeh.2016.03.006" target="_blank" >10.1016/j.yebeh.2016.03.006</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Atypical language representation in children with intractable temporal lobe epilepsy

  • Original language description

    This study evaluated language organization in children with intractable epilepsy caused by temporal lobe focal cortical dysplasia (FCD) alone or dual pathology (temporal lobe FCD and hippocampal sclerosis, HS). We analyzed clinical, neurological, fMRI, neuropsychological, and histopathologic data in 46 pediatric patients with temporal lobe lesions who underwent excisional epilepsy surgery. The frequency of atypical language representation was similar in both groups, but children with dual pathology were more likely to be left-handed. Atypical receptive language cortex correlated with lower intellectual capacity, verbal abstract conceptualization, receptive language abilities, verbal working memory, and a history of status epilepticus but did not correlate with higher seizure frequency or early seizure onset. Histopathologic substrate had only a minor influence on neuropsychological status. Greater verbal comprehension deficits were noted in children with atypical receptive language representation, a risk factor for cognitive morbidity. (C) 2016 Elsevier Inc. All rights reserved.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30502 - Other medical science

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2016

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    EPILEPSY BEHAV

  • ISSN

    1525-5050

  • e-ISSN

    1525-5069

  • Volume of the periodical

    58

  • Issue of the periodical within the volume

    MAY 2016

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    5

  • Pages from-to

    91-96

  • UT code for WoS article

    000376455100016

  • EID of the result in the Scopus database