Oncological Outcomes of Patients with Concomitant Bladder and Urethral Carcinoma
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F16%3A10327971" target="_blank" >RIV/00064203:_____/16:10327971 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11130/16:10327971
Result on the web
<a href="http://dx.doi.org/10.1159/000448335" target="_blank" >http://dx.doi.org/10.1159/000448335</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1159/000448335" target="_blank" >10.1159/000448335</a>
Alternative languages
Result language
angličtina
Original language name
Oncological Outcomes of Patients with Concomitant Bladder and Urethral Carcinoma
Original language description
Introduction: The study aimed to investigate oncological outcomes of patients with concomitant bladder cancer (BC) and urethral carcinoma. Methods: This is a multicenter series of 110 patients (74 men, 36 women) diagnosed with urethral carcinoma at 10 referral centers between 1993 and 2012. Kaplan Meier analysis was used to investigate the impact of BC on survival, and Cox regression multivariable analysis was performed to identify predictors of recurrence. Results: Synchronous BC was diagnosed in 13 (12%) patients, and the median follow-up was 21 months (interquartile range 4-48). Urethral cancers were of higher grade in patients with synchronous BC compared to patients with non-synchronous BC (p = 0.020). Patients with synchronous BC exhibited significantly inferior 3-year recurrence-free survival (RFS) compared to patients with non-synchronous BC (63.2 vs. 34.4%; p = 0.026). In multivariable analysis, inferior RFS was associated with clinically advanced nodal stage (p < 0.001), proximal tumor location (p < 0.001) and synchronous BC (p = 0.020). Conclusion: The synchronous presence of BC in patients diagnosed with urethral carcinoma has a significant adverse impact on RFS and should be an impetus for a multimodal approach. (C) 2016 5. Karger AG, Basel
Czech name
—
Czech description
—
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
—
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Urologia Internationalis
ISSN
0042-1138
e-ISSN
—
Volume of the periodical
97
Issue of the periodical within the volume
2
Country of publishing house
CH - SWITZERLAND
Number of pages
8
Pages from-to
134-141
UT code for WoS article
000382711500002
EID of the result in the Scopus database
2-s2.0-84980383668