Correlation Between Disease Stage and the Presence of Viable Circulating Tumor Cells in Endometrial Cancer

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F18%3A10427543" target="_blank" >RIV/00064203:_____/18:10427543 - isvavai.cz</a>

Alternative codes found

RIV/27283933:_____/18:00006339 RIV/61383082:_____/18:00000462 RIV/00216208:11110/18:10382992 RIV/00064173:_____/18:N0000013

Result on the web

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=hR~zZ7yh6a" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=hR~zZ7yh6a</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.21873/anticanres.12550" target="_blank" >10.21873/anticanres.12550</a>

Result language

angličtina

Original language name

Correlation Between Disease Stage and the Presence of Viable Circulating Tumor Cells in Endometrial Cancer

Original language description

Background/Aim: The presence of circulating tumor cells (CTCs) in the peripheral blood of patients with solid tumors is associated with a poor prognosis. However, there are limited data concerning the detection of CTCs in endometrial cancer (EC). The aim of this study was to evaluate the presence of CTCs in the peripheral blood of patients with EC. Materials and Methods: Peripheral blood samples from 92 patients who underwent a surgical procedure were evaluated using MetaCell (R) separation technology for CTCs. Results: CTCs were detected in 69 (75%) patients with EC. Conclusion: CTCs were detected in a higher percentage of patients than in other studies. The results showed that the technology applied in this study can efficiently capture viable tumor cells in the blood that can be cultured while maintaining their original phenotype. This paper discusses the first successful culturing of human circulating endometrial cancer cells for further downstream functional and molecular characterization.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30204 - Oncology

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Anticancer Research

ISSN

0250-7005

e-ISSN

—

Volume of the periodical

38

Issue of the periodical within the volume

5

Country of publishing house

GR - GREECE

Number of pages

5

Pages from-to

2983-2987

UT code for WoS article

000449923200050

EID of the result in the Scopus database

2-s2.0-85046506490