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Correlation Between Disease Stage and the Presence of Viable Circulating Tumor Cells in Endometrial Cancer

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F18%3A10382992" target="_blank" >RIV/00216208:11110/18:10382992 - isvavai.cz</a>

  • Alternative codes found

    RIV/27283933:_____/18:00006339 RIV/61383082:_____/18:00000462 RIV/00064173:_____/18:N0000013 RIV/00064203:_____/18:10427543

  • Result on the web

    <a href="https://doi.org/10.21873/anticanres.12550" target="_blank" >https://doi.org/10.21873/anticanres.12550</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.21873/anticanres.12550" target="_blank" >10.21873/anticanres.12550</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Correlation Between Disease Stage and the Presence of Viable Circulating Tumor Cells in Endometrial Cancer

  • Original language description

    Background/Aim: The presence of circulating tumor cells (CTCs) in the peripheral blood of patients with solid tumors is associated with a poor prognosis. However, there are limited data concerning the detection of CTCs in endometrial cancer (EC). The aim of this study was to evaluate the presence of CTCs in the peripheral blood of patients with EC. Materials and Methods: Peripheral blood samples from 92 patients who underwent a surgical procedure were evaluated using MetaCell (R) separation technology for CTCs. Results: CTCs were detected in 69 (75%) patients with EC. Conclusion: CTCs were detected in a higher percentage of patients than in other studies. The results showed that the technology applied in this study can efficiently capture viable tumor cells in the blood that can be cultured while maintaining their original phenotype. This paper discusses the first successful culturing of human circulating endometrial cancer cells for further downstream functional and molecular characterization.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30204 - Oncology

Result continuities

  • Project

  • Continuities

    V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Others

  • Publication year

    2018

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Anticancer Research

  • ISSN

    0250-7005

  • e-ISSN

  • Volume of the periodical

    38

  • Issue of the periodical within the volume

    5

  • Country of publishing house

    GR - GREECE

  • Number of pages

    5

  • Pages from-to

    2983-2987

  • UT code for WoS article

    000449923200050

  • EID of the result in the Scopus database

    2-s2.0-85046506490