Tumour volume and radiotherapy prolongation in locally advanced head and neck cancer patients treated with radical IMRT
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F22%3A10430984" target="_blank" >RIV/00064203:_____/22:10430984 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/22:10430984 RIV/00216208:11130/22:10430984 RIV/00064211:_____/22:S0000022 RIV/00064190:_____/21:N0000039
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=UVXxoIiLnS" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=UVXxoIiLnS</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.5507/bp.2021.047" target="_blank" >10.5507/bp.2021.047</a>
Alternative languages
Result language
angličtina
Original language name
Tumour volume and radiotherapy prolongation in locally advanced head and neck cancer patients treated with radical IMRT
Original language description
AIMS: The relationship of tumour volume, radiotherapy treatment time and other prognostic factors affecting prognosis was evaluated. METHODS: 184 patients with locally advanced head and neck cancer were treated with radical intensity modulated radiotherapy (IMRT) and compared retrospectively. RESULTS: In the multivariate analysis the overall survival was dependent on gross tumour volume (GTV), clinical stage (CS), radiotherapy treatment time (RTT) and p16 status. Local control was influenced by GTV, overall RTT and age. DFS was significantly affected by GTV, CS, RTT, p16 status and concomitant chemotherapy (CHT). CONCLUSIONS: The tumour volume and the radiotherapy treatment time were the most significant prognostic factors with the best outcomes in patients with GTV <= 55 cc and RTT <= 48 days (mean LC 8.1, DFS 7.1 and OS 6.4 years) and worst outcomes with GTV > 55 cc and RTT >48 days (mean LC 4.4, mean DFS 3.2 and mean OS 2.6 years).
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30204 - Oncology
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Biomedical Papers
ISSN
1213-8118
e-ISSN
1804-7521
Volume of the periodical
166
Issue of the periodical within the volume
4
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
7
Pages from-to
405-411
UT code for WoS article
000731338500001
EID of the result in the Scopus database
2-s2.0-85143695244