Early initiation of embryo transfers after uterus transplantation to shorten the administration of immunosuppressive therapy

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F22%3A10449808" target="_blank" >RIV/00064203:_____/22:10449808 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11110/22:10449808 RIV/00216208:11130/22:10449808 RIV/00064211:_____/22:S0000029

Result on the web

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=AZfCSSMlbY" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=AZfCSSMlbY</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.48095/cccg2022346" target="_blank" >10.48095/cccg2022346</a>

Result language

angličtina

Original language name

Early initiation of embryo transfers after uterus transplantation to shorten the administration of immunosuppressive therapy

Original language description

Uterus transplantation seems to be a promising method for the causal treatment of absolute uterine factor infertility in women with an absent or non-functional uterus. Since uterus transplantation is still experimental in nature, there are no strict guidelines regarding each step of this comprehensive treatment method. Prior to uterus transplantation, ovarian stimulation and in vitro fertilization are performed on the potential uterus recipient, and the obtained embryos are cryopreserved and stored for the transfers after transplantation when only non-fetotoxic maintenance immunosuppressants are administered. In the first human uterus transplantation study, the start of embryo transfers was set at 12 months after transplantation. Due to the growing experience, especially with early rejections after transplantation and the course of pregnancy, several ongoing studies have experimentally shortened the uterus transplant-to-embryo transfer interval to 6 months. Shortening the total time of immunosuppression administration after uterus transplantation is the main reason for early initiation of embryo transfers after transplantation. However, the safety of an interval of less than one year between uterine transplantation and the first post-transplant embryo transfer should be further studied.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30214 - Obstetrics and gynaecology

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2022

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Česká gynekologie

ISSN

1210-7832

e-ISSN

1805-4455

Volume of the periodical

87

Issue of the periodical within the volume

5

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

4

Pages from-to

346-349

UT code for WoS article

000880378000001

EID of the result in the Scopus database

2-s2.0-85140880584