Hypoglycemia in Diabetes Mellitus Patients with Liver Insufficiency-A Systematic Review
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F25%3A10494853" target="_blank" >RIV/00064203:_____/25:10494853 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11130/25:10494853
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=cvP~Qi_w" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=cvP~Qi_w</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s44411-025-00058-z" target="_blank" >10.1007/s44411-025-00058-z</a>
Alternative languages
Result language
angličtina
Original language name
Hypoglycemia in Diabetes Mellitus Patients with Liver Insufficiency-A Systematic Review
Original language description
Background: Liver insufficiency is a risk factor for hypoglycemia in patients without diabetes. However, the impact of chronic liver disease on hypoglycemia risk in people with diabetes remains unclear. The aim of this study was to systematically review existing literature on hypoglycemic events in diabetes patients with liver insufficiency. Methods: Using the words "diabetes" and "hypoglycemia", "glycemic control", "glucose measurement" and "liver insufficiency", "chronic liver disease", "cirrhosis", "liver impairment", "liver injury", "liver failure", "liver enzyme", we searched Pubmed, Web of Science and Scopus databases for articles in English that contained data on hypoglycemia in diabetes patients with liver insufficiency published until the end of April 2024. Results: A total of 19 studies involving a total of 100,000 patients with diabetes were included. Only two studies looked on the topic in more detail and both suggested hypoglycemia is more common in patients with both liver insufficiency and diabetes. Hypoglycemic events in these patients were often asymptomatic with its associated risks and often nocturnal. Remaining studies were of retrospective design with related limitations, but overall support the hypothesis. Conclusion: The risk of hypoglycemia especially asymptomatic in diabetes patients with liver insufficiency should be taken into account when treating these patients. A comparative study of diabetes patients with and without liver insufficiency is, however, missing.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30202 - Endocrinology and metabolism (including diabetes, hormones)
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Bratislavské lekárske listy / Bratislava Medical Journal
ISSN
0006-9248
e-ISSN
1336-0345
Volume of the periodical
126
Issue of the periodical within the volume
3
Country of publishing house
SK - SLOVAKIA
Number of pages
19
Pages from-to
249-267
UT code for WoS article
001465550900010
EID of the result in the Scopus database
2-s2.0-85217909155