A comparative study between CT angiography and flow parameters in hemodynamic phantom of carotid stenosis evaluated by duplex sonography

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F25%3A10498867" target="_blank" >RIV/00064203:_____/25:10498867 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11110/25:10498867

Result on the web

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=JZiC59sxg4" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=JZiC59sxg4</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1186/s41205-025-00271-0" target="_blank" >10.1186/s41205-025-00271-0</a>

Result language

angličtina

Original language name

A comparative study between CT angiography and flow parameters in hemodynamic phantom of carotid stenosis evaluated by duplex sonography

Original language description

BACKGROUND: The use of 3D-printed hemodynamic phantom of a stenotic carotid artery has not been extensively investigated. Our study aims to address this gap by exploring the correlation between CTA and flow parameters in hemodynamic phantom. METHODS: Patients with carotid stenosis were included in a prospective study. A realistic phantoms of carotid artery stenoses were 3D-printed based on CT angiography. Stenosis severity and hemodynamic flow parameters in the phantom evaluated using duplex sonography were correlated with CTA. The primary outcome was to compare the evaluation of the percentage of stenosis based on the measurement of diameter reduction and area reduction of the carotid artery among CTA, a 3D model constructed from CTA data, and ultrasound measurement of stenosis percentage within the 3D printed phantom. The secondary outcome was to determine whether the percentage of stenosis measured by ultrasound in B-mode or ultrasound-measured flow velocities (PSV, EDV) better correlates with the stenosis percentage derived from CTA and the phantom. RESULTS: The study included 95 subjects (average age 71 years, 75% male) with carotid stenosis, 39% were symptomatic. Significant correlations were found between ultrasound B-Mode findings on the phantom and CTA, with the strongest correlations for area reduction (Spearman r = 0.615, p &lt; 0.0001) and diameter reduction (Spearman r = 0.465, p &lt; 0.0001). The most robust correlation between PSV and EDV in stenosis and the percentage of stenosis was identified between PSV in stenosis and the percentage of stenosis by diameter reduction, as evaluated through ultrasound. The Spearman correlation coefficient revealed a relatively strong correlation, with a value of r = 0.444 (p &lt; 0.0001), and the Kendall Tau correlation coefficient also demonstrated significance, with a value of r = 0.302 (p &lt; 0.0001). CONCLUSIONS: A significant correlation between CTA and duplex sonography measurements on the carotid phantom was demostrated, suggesting the potential utilization of the phantom in testing hemodynamic parameters of carotid stenosis.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30103 - Neurosciences (including psychophysiology)

Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2025

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

3D printing in medicine

ISSN

—

e-ISSN

2365-6271

Volume of the periodical

11

Issue of the periodical within the volume

1

Country of publishing house

DE - GERMANY

Number of pages

12

Pages from-to

29

UT code for WoS article

001510495600001

EID of the result in the Scopus database

2-s2.0-105008227673