Peak systolic velocity ratio for evaluation of internal carotid artery stenosis correlated with plaque morphology: substudy results of the ANTIQUE study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15120%2F23%3A73625320" target="_blank" >RIV/61989592:15120/23:73625320 - isvavai.cz</a>

Alternative codes found

RIV/61988987:17110/23:A2402LZZ RIV/47813059:19520/23:A0000408 RIV/00216208:11150/23:10471773 RIV/00179906:_____/23:10471773 and 2 more

Result on the web

<a href="https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2023.1206483/full" target="_blank" >https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2023.1206483/full</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3389/fneur.2023.1206483" target="_blank" >10.3389/fneur.2023.1206483</a>

Result language

angličtina

Original language name

Peak systolic velocity ratio for evaluation of internal carotid artery stenosis correlated with plaque morphology: substudy results of the ANTIQUE study

Original language description

Background: Accurate assessment of carotid stenosis severity is important for proper patient management. The present study aimed to compare the evaluation of carotid stenosis severity using four duplex sonography (DUS) measurements, including peak systolic velocity (PSV), PSV ratio in stenosis and distal to stenosis (PSVICA/ICA ratio), end-diastolic velocity (EDV), and B-mode, with computed tomography angiography (CTA), and to evaluate the impact of plaque morphology on correlation between DUS and CTA. Methods: Consecutive patients with carotid stenosis of ≥40% examined using DUS and CTA were included. Plaque morphology was also determined using magnetic resonance imaging. Spearman’s correlation and Kendall’s rank correlation were used to evaluate the results. Results: A total of 143 cases of internal carotid artery stenosis of ≥40% based on DUS were analyzed. The PSVICA/ICA ratio showed the highest correlation [Spearman’s correlation r = 0.576) with CTA, followed by PSV (r = 0.526), B-mode measurement (r = 0.482), and EDV (r = 0.441; p &lt; 0.001 in all cases]. The worst correlation was found for PSV when the plaque was calcified (r = 0.238), whereas EDV showed a higher correlation (r = 0.523). Correlations of B-mode measurement were superior for plaques with smooth surface (r = 0.677), while the PSVICA/ICA ratio showed the highest correlation in stenoses with irregular (r = 0.373) or ulcerated (r = 0.382) surfaces, as well as lipid (r = 0.406), fibrous (r = 0.461), and mixed (r = 0.403; p &lt; 0.01 in all cases) plaques. Nevertheless, differences between the mentioned correlations were not statistically significant (p &gt; 0.05 in all cases). Conclusion: PSV, PSVICA/ICA ratio, EDV, and B-mode measurements showed comparable correlations with CTA in evaluation of carotid artery stenosis based on their correlation with CTA results. Heavy calcifications and plaque surface irregularity or ulceration negatively influenced the measurement accuracy.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30210 - Clinical neurology

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2023

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Frontiers in Neurology

ISSN

1664-2295

e-ISSN

1664-2295

Volume of the periodical

14

Issue of the periodical within the volume

November

Country of publishing house

CH - SWITZERLAND

Number of pages

9

Pages from-to

1206483

UT code for WoS article

001105742200001

EID of the result in the Scopus database

2-s2.0-85177240838