Immunogenicity and safety of Pandemic H1N1 2009 Influenza vaccine for HIV-1 patients

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064211%3A_____%2F12%3A%230000136" target="_blank" >RIV/00064211:_____/12:#0000136 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.4149/av_2012_04_349" target="_blank" >http://dx.doi.org/10.4149/av_2012_04_349</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Immunogenicity and safety of Pandemic H1N1 2009 Influenza vaccine for HIV-1 patients

Original language description

The advent of the 2009 H1N1 pandemic influenza has raised concerns about the immunogenicity and safety of vaccines against the new virus, especially in immunocompromised individuals. In our study we evaluated the immunogenicity and safety of pandemic influenza vaccine in 34 HIV-1 infected patients. Antibody production was tested by hemagglutinin inhibition assay according to the World Health Organization methodology. No serious adverse event was observed among the vaccinees, only nine individuals (26.5%) reported moderate pain at the application site lasting maximally two days. The protection rate after vaccination of HIV-1 infected individuals with a single dose of studied pandemic H1N1 influenza vaccine, albeit low if compared with normal population,met the criteria set by European Committee for Medicinal Products for minimal immunogenicity.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FN - Epidemiology, infection diseases and clinical immunology

OECD FORD branch

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Project

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Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Acta virologica

ISSN

1336-2305

e-ISSN

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Volume of the periodical

56

Issue of the periodical within the volume

4

Country of publishing house

SK - SLOVAKIA

Number of pages

3

Pages from-to

349-351

UT code for WoS article

000313403400011

EID of the result in the Scopus database

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