Evaluation of Oncological Safety of Fat Grafting After Breast-Conserving Therapy: A Prospective Study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064211%3A_____%2F16%3AN0000019" target="_blank" >RIV/00064211:_____/16:N0000019 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11110/16:10316870

Result on the web

<a href="https://www.ncbi.nlm.nih.gov/pubmed/26467459" target="_blank" >https://www.ncbi.nlm.nih.gov/pubmed/26467459</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1245/s10434-015-4908-2" target="_blank" >10.1245/s10434-015-4908-2</a>

Result language

angličtina

Original language name

Evaluation of Oncological Safety of Fat Grafting After Breast-Conserving Therapy: A Prospective Study

Original language description

Introduction. Breast-conserving treatment (BCT) consisting of a lumpectomy followed by radiation is considered the standard of care in early-stage breast cancer, and breast reconstruction using fat transfer has become the standard of care in these patients. Immediately following BCT, patients are theoretically the most prone for cancer recurrence caused by the remaining mass of glandular tissue. Therefore, we conducted a prospective study to evaluate the oncological safety of fat grafting in patients after BCT. Methods. We analyzed patients who underwent breast reconstruction after BCT between April 2011 and February 2014. The control subjects were matched from a prospective database of women treated for breast cancer who did not undergo fat grafting, and each control was matched for the following variables: date of primary cancer surgery, date of fat grafting, histology, estrogen and progesterone receptors (ER+PR), adjuvant hormone therapy, disease-free interval from primary operation (BCT), and disease-free interval from breast reconstruction involving fat grafting. The primary endpoint of this study was tumor recurrence. Results. The study group consisted of 32 patients, while the control group consisted of 45 patients. Breast tumor recurrence was observed in 2 of 32 cases (6.25 %) in the reconstruction group, and distant metastases were detected in both cases. In the control group without reconstruction, we found cancer recurrence in 2 of 41 cases (4.88 %), and locoregional recurrence was observed in both cases. The difference in cancer recurrence after BCT was insignificant between groups (p = 0.593).

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

ANNALS OF SURGICAL ONCOLOGY

ISSN

1068-9265

e-ISSN

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Volume of the periodical

23

Issue of the periodical within the volume

3

Country of publishing house

US - UNITED STATES

Number of pages

6

Pages from-to

776-781

UT code for WoS article

000371334600012

EID of the result in the Scopus database

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