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Digital cholangioscopy: the diagnostic yield and impact on management of patients with indeterminate biliary stricture

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00098892%3A_____%2F18%3AN0000031" target="_blank" >RIV/00098892:_____/18:N0000031 - isvavai.cz</a>

  • Alternative codes found

    RIV/61989592:15110/18:73587895

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Digital cholangioscopy: the diagnostic yield and impact on management of patients with indeterminate biliary stricture

  • Original language description

    Objectives: Biliary strictures frequently present a diagnostic challenge. The aim of this study was to evaluate the impact of digital single-operator cholangioscopy (DSOC) on subsequent treatment of patients with biliary stricture. Methods: Consecutive patients undergoing DSOC for biliary stricture were enrolled. Gold standard for final diagnosis included histology from surgical resection. In patients without surgery, clinical evaluation methods and repeated imaging studies were used for comparison of DSOC findings and final diagnosis. Patients were followed-up prospectively focusing on subsequent treatment. Results: Among 30 enrolled patients, final diagnosis was malignant in 13 (43 %) and benign in 17 (57 %). The sensitivity and specificity of visual impression in diagnosing malignant stricture were 100% (95% CI: 75 − 100) and 76% (95% CI: 50 − 93), respectively. The sensitivity and specificity for biopsy were 92% (95 % CI: 62 − 100) and 100 % (95 % CI: 78 − 100), respectively. One (3 %) case of complicating cholangitis with fatal outcome occurred. Final treatment included surgery in 7 (23 %), endoscopy in 18 (60 %) and chemotherapy in 3 (10 %) of patients. Conclusions: In this study, favorable operating characteristics of DSOC were confirmed. Absolute negative predictive value of visual impression provided reassurance to patients with benign strictures who avoided unnecessary surgery in 53 %. One (3 %) case of cholangitis with fatal outcome occurred

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>SC</sub> - Article in a specialist periodical, which is included in the SCOPUS database

  • CEP classification

  • OECD FORD branch

    30219 - Gastroenterology and hepatology

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2018

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Scandinavian Journal of Gastroenterology

  • ISSN

    0036-5521

  • e-ISSN

  • Volume of the periodical

    53

  • Issue of the periodical within the volume

    10-11

  • Country of publishing house

    NO - NORWAY

  • Number of pages

    4

  • Pages from-to

    1364-1367

  • UT code for WoS article

  • EID of the result in the Scopus database

    2-s2.0-85055480777