Digital cholangioscopy: the diagnostic yield and impact on management of patients with biliary stricture

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F18%3A10388140" target="_blank" >RIV/00216208:11150/18:10388140 - isvavai.cz</a>

Result on the web

<a href="https://doi.org/10.1080/00365521.2018.1512649" target="_blank" >https://doi.org/10.1080/00365521.2018.1512649</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1080/00365521.2018.1512649" target="_blank" >10.1080/00365521.2018.1512649</a>

Result language

angličtina

Original language name

Digital cholangioscopy: the diagnostic yield and impact on management of patients with biliary stricture

Original language description

OBJECTIVES:Biliary strictures frequently present a diagnostic challenge. The aim of this study was to evaluate the impact of digital single-operator cholangioscopy (DSOC) on subsequent treatment of patients with biliary stricture.METHODS:Consecutive patients undergoing DSOC for biliary stricture were enrolled. Gold standard for final diagnosis included histology from surgical resection. In patients without surgery, clinical evaluation methods and repeated imaging studies were used for comparison of DSOC findings and final diagnosis. Patients were followed-up prospectively focusing on subsequent treatment.RESULTS:Among 30 enrolled patients, final diagnosis was malignant in 13 (43%) and benign in 17 (57%). The sensitivity and specificity of visual impression in diagnosing malignant stricture were 100% (95% CI: 75 - 100) and 76% (95% CI: 50 - 93), respectively. The sensitivity and specificity for biopsy were 92% (95% CI: 62 - 100) and 100% (95% CI: 78 - 100), respectively. One (3%) case of complicating cholangitis with fatal outcome occurred. Final treatment included surgery in 7 (23%), endoscopy in 18 (60%) and chemotherapy in 3 (10%) of patients.CONCLUSIONS:In this study, favorable operating characteristics of DSOC were confirmed. Absolute negative predictive value of visual impression provided reassurance to patients with benign strictures who avoided unnecessary surgery in 53%. One (3%) case of cholangitis with fatal outcome occurred.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30219 - Gastroenterology and hepatology

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Scandinavian Journal of Gastroenterology

ISSN

0036-5521

e-ISSN

—

Volume of the periodical

53

Issue of the periodical within the volume

10-11

Country of publishing house

GB - UNITED KINGDOM

Number of pages

4

Pages from-to

1364-1367

UT code for WoS article

000457980900032

EID of the result in the Scopus database

2-s2.0-85055480777