Mechanical thrombectomy in patients with acute ischemic stroke on anticoagulation therapy

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00098892%3A_____%2F18%3AN0000101" target="_blank" >RIV/00098892:_____/18:N0000101 - isvavai.cz</a>

Alternative codes found

RIV/61989592:15110/18:73591721

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Mechanical thrombectomy in patients with acute ischemic stroke on anticoagulation therapy

Original language description

Mechanical thrombectomy (MT) for acute ischemic stroke (IS) can be performed also in patients on anticoagulation therapy (AT); however, sufficient and reliable data about safety and efficacy of MT are still missing. Thus, we aimed to compare these parameters between patients treated on AT and without AT. All consecutive IS patients treated with MT using stent retrievers were included in the retrospective analysis. Neurological deficit was scored using National Institutes of Health Stroke Scale (NIHSS) and 90-day clinical outcome using modified Rankin scale with a score 0-2 for good outcome. Recanalization was rated using Thrombolysis in Cerebral Infarction (TICI) scale. Symptomatic intracerebral hemorrhage (SICH) was assessed according to the SITS-MOST criteria. Out of 703 patients treated with MT, 88 (12.5 %) patients (46 % males, mean age 75.5 years) were on AT with an admission median NIHSS of 17 points. Recanalization (TICI 2b-3) was achieved in 80 % and complete (TICI 3) in 65 % of patients on AT and in 80 and 65 % of patients without AT (p-1.000). SICH after MT was detected in 9 % of AT and 5 % of non-AT patients (p-0.136). Good outcome was present in 36 % of AT patients (p-0.03). AT patients with poor outcome had more frequently atrial fibrillation (93 %, p-0.005), higher admission NIHSS (17, p-0.004) and higher rate of SICH (14.5 %, p-0.047). MT seems to be safe also in patients on AT. Poor outcome may be related to higher admission NIHSS, higher rate of SICH and presence of atrial fibrillation

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30210 - Clinical neurology

Project

<a href="/en/project/NV17-30101A" target="_blank" >NV17-30101A: Risk factors of ischemic stroke in young patients and relation with epidemiologic, social and economic parameters and life style</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Cardiovascular and Interventional Radiology

ISSN

0174-1551

e-ISSN

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Volume of the periodical

41

Issue of the periodical within the volume

5

Country of publishing house

US - UNITED STATES

Number of pages

6

Pages from-to

706-711

UT code for WoS article

000428802400006

EID of the result in the Scopus database

2-s2.0-85042081336