Early isolated central nervous system relapse of mantle cell lymphoma successfully treated with ibrutinib and CAR T-cell therapy
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00098892%3A_____%2F25%3A10159782" target="_blank" >RIV/00098892:_____/25:10159782 - isvavai.cz</a>
Alternative codes found
RIV/61989592:15110/25:73634883
Result on the web
<a href="https://redakce.carecomm.cz/tahd/cs/article/view/3023" target="_blank" >https://redakce.carecomm.cz/tahd/cs/article/view/3023</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.48095/cctahd202526" target="_blank" >10.48095/cctahd202526</a>
Alternative languages
Result language
angličtina
Original language name
Early isolated central nervous system relapse of mantle cell lymphoma successfully treated with ibrutinib and CAR T-cell therapy
Original language description
Mantle cell lymphoma (MCL) is a relatively rare and clinically distinct subtype of non-Hodgkin lymphoma. Involvement of the central nervous system is an uncommon manifestation at both diagnosis and recurrence. Central nervous system (CNS) relapse more frequently occurs in the context of aggressive dis ease behaviour and portends a poor prognosis. However, advances in therapeutic strategies for MCL have opened the possibility of achieving durable remission, even in this high-risk presentation. We report a case of a patient who developed an early, isolated CNS relapse following autologous stem cell transplantation. The patient was successfully treated with a sequential treatment protocol combining chemoimmunotherapy, ibrutinib and chimeric antigen receptor T-cell therapy.
Czech name
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Czech description
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Classification
Type
J<sub>SC</sub> - Article in a specialist periodical, which is included in the SCOPUS database
CEP classification
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OECD FORD branch
30205 - Hematology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Transfuze a hematologie dnes
ISSN
1213-5763
e-ISSN
1805-4587
Volume of the periodical
31
Issue of the periodical within the volume
4
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
5
Pages from-to
311-315
UT code for WoS article
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EID of the result in the Scopus database
2-s2.0-105028566250