Effects of exposure to three environmental chemicals on the selected biochemical parameters of the blood plasma of rainbow trout, Oncorhynchus mykiss (Walbaum)

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00100595%3A_____%2F16%3AN0000043" target="_blank" >RIV/00100595:_____/16:N0000043 - isvavai.cz</a>

Result on the web

<a href="https://www.degruyter.com/downloadpdf/j/cszma.2016.65.issue-1/cszma-2016-0002/cszma-2016-0002.pdf" target="_blank" >https://www.degruyter.com/downloadpdf/j/cszma.2016.65.issue-1/cszma-2016-0002/cszma-2016-0002.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1515/cszma-2016-0002" target="_blank" >10.1515/cszma-2016-0002</a>

Result language

angličtina

Original language name

Effects of exposure to three environmental chemicals on the selected biochemical parameters of the blood plasma of rainbow trout, Oncorhynchus mykiss (Walbaum)

Original language description

Rainbow trout Oncorhynchus mykiss at a weight of 115 ± 24 g (mean ± SD) were experimentally injected with di(2-ethylhexyl)phthalate (DEHP), 2,3,7,8-tetrachlorodibenzo-p-dioxine (TCDD) and gamma isomer of hexachlorocyclohexane (γ-HCH ) to evaluate nitrogen metabolism (total protein [TP], blood urea nitrogen, uric acid [UA], creatinine), carbohydrate metabolism (glucose), mineral metabolism (inorganic phosphate[P], total calcium [Cat]), and catalytic activity of enzymes (alanine aminotransferase [ALT], aspartate aminotransferase [AST], alkaline phosphatase [ALP], lactate dehydrogenase [LD]). After 21 days, the tested xenobiotics, administered by the intraperitoneally route, caused the following effect: in comparison with negative controls, fish injected with DEHP at concentrations of 200 or 50 mg kg-1 of body weight were found to have a higher level of P and lower level of Cat and decreased catalytic concentrations of ALT, AST, ALP and LD in the plasma of the peripheral blood. A higher level of TP and P and a decreased catalytic concentration of ALT were found when TCDD was administered at a dose of 2 μg kg-1. A decrease in the catalytic concentrations of ALT and ALP occurred in fish injected with γ-HCH in a dose of 50 mg kg-1. UA and P levels were decreased in fish injected with γ-HCH in a dose of 5 mg kg-1.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

GL - Fishery

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Acta Musei Silesiae, Scientiae Naturales

ISSN

2336-3193

e-ISSN

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Volume of the periodical

65

Issue of the periodical within the volume

1

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

18

Pages from-to

15-32

UT code for WoS article

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EID of the result in the Scopus database

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