High-normal blood pressure is associated with increased resting sympathetic activity but normal responses to stress tests

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F13%3A00060553" target="_blank" >RIV/00159816:_____/13:00060553 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.3109/08037051.2012.759689" target="_blank" >http://dx.doi.org/10.3109/08037051.2012.759689</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3109/08037051.2012.759689" target="_blank" >10.3109/08037051.2012.759689</a>

Result language
angličtina
Original language name
High-normal blood pressure is associated with increased resting sympathetic activity but normal responses to stress tests
Original language description
High-normal blood pressure (BP) increases the risk of cardiovascular (CV) disease. The mechanisms underlying this increased risk are not clear. Sympathetic activation appears to be a potential mechanism linking high-normal BP to CV disease. This study examined whether high-normal BP compared with optimal BP is linked to sympathoexcitation at rest and/or during laboratory stressors. Methods. Heart rate (HR), BP and muscle sympathetic nerve activity (MSNA) were obtained at rest and during stress tests (sustained handgrip and mental stress) in 18 subjects (15 males and three females) with high-normal BP (systolic BP of 130 -139 mmHg, diastolic BP of 85 -89 mmHg, or both) and in 12 subjects (10 males and two females) with optimal BP (<120/80 mmHg) matchedfor age (34 +/- 3 years in both groups) and body mass index (25 +/- 2 kg/m(2) in both groups). Results. Despite the higher resting BP levels, MSNA was higher in subjects with high-normal BP than in the optimal BP group (26 +/- 3 vs 18 +/-
Czech name
—
Czech description
—

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FA - Cardiovascular diseases including cardio-surgery
OECD FORD branch
—

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)