Combined therapy of mixed dyslipidemia in patients with high cardiovaskular risk and changes in tne lipid target values and atherogenic index of plasma

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F14%3A00061277" target="_blank" >RIV/00159816:_____/14:00061277 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1016/j.crvasa.2014.01.003" target="_blank" >http://dx.doi.org/10.1016/j.crvasa.2014.01.003</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.crvasa.2014.01.003" target="_blank" >10.1016/j.crvasa.2014.01.003</a>

Result language

angličtina

Original language name

Combined therapy of mixed dyslipidemia in patients with high cardiovaskular risk and changes in tne lipid target values and atherogenic index of plasma

Original language description

Purpose: To evaluate the safety and efficacy of combined lipid-modifying agents (statin + fenofibrate) on plasma lipid profile including the atherogenic index of plasma (AIP = log [TG/HDL-C]) in patients at high and very high cardiovascular (CV) risk andmixed dyslipi-demia. Method: A total of 81 patients (53 males, 28 females; 60 +- 9.8 years) were included. Mixed dyslipidemia was defined as having 2 of the following 3 lipid abnormalities: LDL-cholesterol (C) >2.5 mmol/l, HDL-C <1.0 mmol/l in males and<1.3 mmol/l in females, triglycerides (TG) >1.7 mmol/l. Global CV risk was estimated according to the current European guidelines. Management with fenofibrate (160-267 mg) + atorvastatin (10-20 mg) or simvastatin (20- 40 mg) was indicated for 6 months.Males and females were stratified according to the AIP risk categories: AIP <0.11 (low risk), AIP >0.21 (high risk). Results: About 3/4 of high or very high CV risk patients with mixed dyslipidemia (n = 81) suffer from impaired glucose me

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FA - Cardiovascular diseases including cardio-surgery

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Cor et Vasa

ISSN

0010-8650

e-ISSN

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Volume of the periodical

56

Issue of the periodical within the volume

2

Country of publishing house

GB - UNITED KINGDOM

Number of pages

7

Pages from-to

"e133"-"e139"

UT code for WoS article

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EID of the result in the Scopus database

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