Combined therapy of mixed dyslipidemia in patients with high cardiovascular risk and changes in the lipid target values and atherogenic index of plasma

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10227302" target="_blank" >RIV/00216208:11110/14:10227302 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14110/14:00075601 RIV/00216208:11140/14:10227302 RIV/00179906:_____/14:10227302 RIV/00669806:_____/14:10227302 RIV/00064165:_____/14:10227302

Result on the web

<a href="http://www.sciencedierect.com/science/article/pii/S0010865014000125" target="_blank" >http://www.sciencedierect.com/science/article/pii/S0010865014000125</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.crvasa.2014.01.003" target="_blank" >10.1016/j.crvasa.2014.01.003</a>

Result language

angličtina

Original language name

Combined therapy of mixed dyslipidemia in patients with high cardiovascular risk and changes in the lipid target values and atherogenic index of plasma

Original language description

To evaluate the safety and efficacy of combined lipid-modifying agents (statin + fenofibrate) in 81 patients (53 males and 28 females) with high or very high cardiovascular risk (according to the SCORE risk chart) and mixed dyslipidemia, which was defined as having 2 of the following 3 lipid abnormalities in mmol/l: LDL-cholesterol (ch) more than 2.5, HDL-ch less than 1 in males and 1,2 in females, triglycerides (TG) more than 1.7. About 44% of those patients had type 2 diabetes mellitus and 30% had impaired fasting glucose. Six-month combined therapy was tolerated very well and reduced LDL-ch by 29%, TG by 40% but HDL-ch increase was noty significant (by 3%). Atherogenic index of plasma: AIP = log(TG/HDL-ch), was decreased significantly in the majority of the patients. It is clear from the study,that more intensive managements of mixed dyslipidemia is needed in those patients.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FA - Cardiovascular diseases including cardio-surgery

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Cor et Vasa

ISSN

0010-8650

e-ISSN

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Volume of the periodical

56

Issue of the periodical within the volume

2

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

7

Pages from-to

"e133"-"e139"

UT code for WoS article

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EID of the result in the Scopus database

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