Vasospasm of the Flap Pedicle: The Effect of 11 of the Most Often Used Vasodilating Drugs. Comparative Study in a Rat Model
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F14%3A00061518" target="_blank" >RIV/00159816:_____/14:00061518 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14110/14:00080165
Result on the web
<a href="http://dx.doi.org/10.1097/PRS.0000000000000570" target="_blank" >http://dx.doi.org/10.1097/PRS.0000000000000570</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1097/PRS.0000000000000570" target="_blank" >10.1097/PRS.0000000000000570</a>
Alternative languages
Result language
angličtina
Original language name
Vasospasm of the Flap Pedicle: The Effect of 11 of the Most Often Used Vasodilating Drugs. Comparative Study in a Rat Model
Original language description
Background: There has been no review study published yet comparing the effects of the vasodilating drugs that are most often used in clinical practice empirically. The aim of the authors' study was to perform this comparison and to select the drugs thatare able to release vasospasm and the drugs that reduce vasospasm duration most effectively in an experimental model in vivo. Methods: Pedicled groin flaps were dissected in 300 male Wistar rats. Vasospasm was induced by tension applied on the pedicle inthe axial direction using a 15-g weight. The blood perfusion of the flap was monitored using a laser Doppler device. The duration of vasospasm was defined as the time from the release of tension until blood flow began to rise. These times were detectedusing automated computerized detection. The effects of 11 different drugs were studied in 14 groups. The drugs were applied locally; some of them were tested in different concentrations or applied parenterally. Results: Ten percent magnes
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FJ - Surgery including transplantology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/NR8368" target="_blank" >NR8368: Vasospams of Microsurgical Free Flaps and Possibilities of Treatment</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Plastic and Reconstructive Surgery
ISSN
0032-1052
e-ISSN
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Volume of the periodical
134
Issue of the periodical within the volume
4
Country of publishing house
US - UNITED STATES
Number of pages
11
Pages from-to
"574E"-"584E"
UT code for WoS article
000343105400009
EID of the result in the Scopus database
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