Microfluidic Organ/Body-on-a-Chip Devices at the Convergence of Biology and Microengineering

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F15%3A00063776" target="_blank" >RIV/00159816:_____/15:00063776 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.3390/s151229848" target="_blank" >http://dx.doi.org/10.3390/s151229848</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/s151229848" target="_blank" >10.3390/s151229848</a>

Result language

angličtina

Original language name

Microfluidic Organ/Body-on-a-Chip Devices at the Convergence of Biology and Microengineering

Original language description

Recent advances in biomedical technologies are mostly related to the convergence of biology with microengineering. For instance, microfluidic devices are now commonly found in most research centers, clinics and hospitals, contributing to more accurate studies and therapies as powerful tools for drug delivery, monitoring of specific analytes, and medical diagnostics. Most remarkably, integration of cellularized constructs within microengineered platforms has enabled the recapitulation of the physiological and pathological conditions of complex tissues and organs. The so-called "organ-on-a-chip" technology, which represents a new avenue in the field of advanced in vitro models, with the potential to revolutionize current approaches to drug screening andtoxicology studies. This review aims to highlight recent advances of microfluidic-based devices towards a body-on-a-chip concept, exploring their technology and broad applications in the biomedical field.

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CG - Electrochemistry

OECD FORD branch

—

Project

<a href="/en/project/ED1.100%2F02%2F0123" target="_blank" >ED1.100/02/0123: St. Anne´s University Hospital Brno - International Clinical Research Center (FNUSA-ICRC)</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Sensors

ISSN

1424-8220

e-ISSN

—

Volume of the periodical

15

Issue of the periodical within the volume

12

Country of publishing house

CH - SWITZERLAND

Number of pages

28

Pages from-to

31142-31170

UT code for WoS article

000367539100086

EID of the result in the Scopus database

—