Performance and complications of lumbar puncture in memory clinics: Results of the multicenter lumbar puncture feasibility study

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F16%3A00063386" target="_blank" >RIV/00159816:_____/16:00063386 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11130/16:10323731 RIV/00064203:_____/16:10323731
Result on the web
<a href="http://dx.doi.org/10.1016/j.jalz.2015.08.003" target="_blank" >http://dx.doi.org/10.1016/j.jalz.2015.08.003</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.jalz.2015.08.003" target="_blank" >10.1016/j.jalz.2015.08.003</a>

Result language
angličtina
Original language name
Performance and complications of lumbar puncture in memory clinics: Results of the multicenter lumbar puncture feasibility study
Original language description
INTRODUCTION: Lumbar puncture (LP) is increasingly performed in memory clinics. We investigated patient-acceptance of LP, incidence of and risk factors for post-LP complications in memory clinic populations. METHODS: We prospectively enrolled 3868 patients (50% women, age 66 +- 11 years, mini mental state examination 25 +- 5) at 23 memory clinics. We used logistic regression analysis using generalized estimated equations to investigate risk factors for post-LP complications, such as typical postlumbar puncture headache (PLPH) and back pain. RESULTS: A total of 1065 patients (31%) reported post-LP complaints; 589 patients (17%) reported back pain, 649 (19%) headache, of which 296 (9%) reported typical PLPH. Only few patients needed medical intervention: 11 (0.3%) received a blood patch, 23 (0.7%) were hospitalized. The most important risk factor for PLPH was medical history of headache. An atraumatic needle and age >65 years were preventive. Gender, rest after LP, or volume of cerebrospinal fluid had no effect. DISCUSSIONS: The overall risk of complications is relatively low. If risk factors shown in this study are taken into account, LPs can be safely performed in memory clinics.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Project
<a href="/en/project/ED1.100%2F02%2F0123" target="_blank" >ED1.100/02/0123: St. Anne´s University Hospital Brno - International Clinical Research Center (FNUSA-ICRC)</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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