Prognosis of Good syndrome: mortality and morbidity of thymoma associated immunodeficiency in perspective
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F16%3A00065741" target="_blank" >RIV/00159816:_____/16:00065741 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14110/16:00090643
Result on the web
<a href="http://www.sciencedirect.com/science/article/pii/S1521661616302509" target="_blank" >http://www.sciencedirect.com/science/article/pii/S1521661616302509</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.clim.2016.07.025" target="_blank" >10.1016/j.clim.2016.07.025</a>
Alternative languages
Result language
angličtina
Original language name
Prognosis of Good syndrome: mortality and morbidity of thymoma associated immunodeficiency in perspective
Original language description
Good syndrome (GS) or thymoma-associated immunodeficiency, is a rare condition that has only been studied in retrospective case series. General consensus was that GS has a worse prognosis than other humoral immunodeficiencies. In this study, physicians of GS patients completed two questionnaires with a two year interval with data on 47 patients, 499 patient years in total. Results on epidemiology, disease characteristics, and outcome are presented. Mean age at diagnosis was 60 years and median follow-up from onset of symptoms was 9 years. There was a high frequency of respiratory tract infections due to encapsulated bacteria. Median survival was 14 years. Survival was reduced compared to age-matched population controls (5-year survival: 82% versus 95%, p = 0.008). In this cohort survival was not associated with gender (HR 0.9, 95% CI 0.3-3.0), autoimmune diseases (HR 2.9, 95% CI 0.8-10.1) or immunosuppressive use (HR 0.3, 95% CI: 0.1-1.2). (C) 2016 The Authors. Published by Elsevier Inc.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FN - Epidemiology, infection diseases and clinical immunology
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Clinical Immunology
ISSN
1521-6616
e-ISSN
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Volume of the periodical
171
Issue of the periodical within the volume
October
Country of publishing house
US - UNITED STATES
Number of pages
6
Pages from-to
12-17
UT code for WoS article
000386195100002
EID of the result in the Scopus database
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