Mesenchymal Stem Cells Immune Properties As Sensors Of Microenvironment

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F16%3A00066036" target="_blank" >RIV/00159816:_____/16:00066036 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Mesenchymal Stem Cells Immune Properties As Sensors Of Microenvironment
Original language description
Tissue inflammation leads to the recruitment and activation of several cell types, which cooperate to create a particular microenvironment that determines the regression of the pathology or its perpetuation (chronic inflammation). Mesenchymal stem cells (MSCs) are multipotent cells present in the stromal fraction of many tissues (i.e umbilical cord blood, placenta, adipose tissue). Several studies are now showing MSCs potential in tissue engineering, especially because of their ability to differentiate onto nanostructure surface. However the effect of nanostructure on MSCs immune properties is not properly characterized. The aim of the project is to develop MSCs reporter lines for transcription factors associated to inflammation, in order to monitor their activity once the cells are seeded onto nanostructure. This will be helpful to understand which materials are more suitable in term of tissue regeneration
Czech name
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Czech description
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Project
<a href="/en/project/LQ1605" target="_blank" >LQ1605: Translational Medicine</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
8TH INTERNATIONAL CONFERENCE ON NANOMATERIALS - RESEARCH & APPLICATION (NANOCON 2016)
ISBN
978-80-87294-71-0
ISSN
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e-ISSN
neuvedeno
Number of pages
4
Pages from-to
435-438
Publisher name
TANGER Ltd.
Place of publication
Ostrava
Event location
Brno
Event date
Oct 19, 2016
Type of event by nationality
EUR - Evropská akce
UT code for WoS article
000410656100076

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