Motion and emotion: anxiety-axial connections in Parkinson's disease

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F17%3A00066263" target="_blank" >RIV/00159816:_____/17:00066263 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14110/17:00095993 RIV/00216208:11110/17:10362023 RIV/61989592:15110/17:73583289 RIV/00064165:_____/17:10362023

Result on the web

<a href="http://dx.doi.org/10.1007/s00702-016-1652-0" target="_blank" >http://dx.doi.org/10.1007/s00702-016-1652-0</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00702-016-1652-0" target="_blank" >10.1007/s00702-016-1652-0</a>

Result language

angličtina

Original language name

Motion and emotion: anxiety-axial connections in Parkinson's disease

Original language description

Anxiety is a serious and frequent complication in Parkinson&apos;s disease (PD) that significantly affects the quality of life of patients. Multiple neuroanatomical, experimental, and clinical studies suggest its close association with axial disturbances. However, whether this relation applies for PD patients (commonly suffering from axial difficulties, such as balance and gait disturbance) has not been properly tested yet. The purpose of this study was to determine whether PD patients suffering from axial symptoms have higher levels of anxiety than others and to identify other factors associated with anxiety-axial connections. In this questionnaire study, 212 patients with PD were assessed by standardized scales, such as Hamilton Anxiety Scale, Montgomery-Asberg Depression Rating Scale, Montreal Cognitive Assessment, examining their mood and cognitive status. These data were correlated to dominant motor symptoms of these patients, such as tremor, rigidity, bradykinesia, and axial symptoms. Unlike other motor symptoms, only axial symptoms showed to be significantly related to higher levels of anxiety. The patients suffering from anxiety and axial problems have also shown significantly higher depression levels. Axial disturbances are related to higher anxiety levels in PD patients. It is crucial to pay high attention to symptoms of anxiety in patients having postural instability or gait disorder. Further clinical studies are desirable to investigate new, practical implications of anxiety-axial connection to provide complex management options of these serious symptoms.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30103 - Neurosciences (including psychophysiology)

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Neural Transmission

ISSN

0300-9564

e-ISSN

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Volume of the periodical

124

Issue of the periodical within the volume

3

Country of publishing house

AT - AUSTRIA

Number of pages

9

Pages from-to

369-377

UT code for WoS article

000394433100009

EID of the result in the Scopus database

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