The contribution of white matter lesions to Parkinson's disease motor and gait symptoms: a critical review of the literature

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F16%3A00089148" target="_blank" >RIV/00216224:14740/16:00089148 - isvavai.cz</a>

Result on the web

<a href="http://link.springer.com/article/10.1007%2Fs00702-015-1470-9" target="_blank" >http://link.springer.com/article/10.1007%2Fs00702-015-1470-9</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00702-015-1470-9" target="_blank" >10.1007/s00702-015-1470-9</a>

Result language

angličtina

Original language name

The contribution of white matter lesions to Parkinson's disease motor and gait symptoms: a critical review of the literature

Original language description

White matter lesions (WML) associated with cerebrovascular disease (CVD) may be observed on magnetic resonance imaging in Parkinson's disease (PD) patients. WML are an important factor contributing to postural, gait, and cognitive impairment in the elderly without PD and worsening the course of Alzheimer's disease (AD). Numerous articles are available on this topic. Whether WML modify and negatively influence the clinical symptoms, and course of PD is a subject of debate. The aim of this review is to examine the available literature on the contribution of WML to PD motor symptoms in relation to clinical characteristics and methods of assessing WML on MRI. After reviewing the database, we identified 19 studies reporting the relationship between WML and PD; ten studies focusing on the impact of WML on the cognitive status in PD were excluded. We analysed altogether nine studies reporting the relationship between WML and motor signs of PD.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Neural Transmission

ISSN

0300-9564

e-ISSN

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Volume of the periodical

123

Issue of the periodical within the volume

3

Country of publishing house

AT - AUSTRIA

Number of pages

10

Pages from-to

241-250

UT code for WoS article

000373162900010

EID of the result in the Scopus database

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