Prevalence and Predictors of Early Heart Failure with Preserved Ejection Fraction in Patients with Paroxysmal Atrial Fibrillation
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F17%3A00066885" target="_blank" >RIV/00159816:_____/17:00066885 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14110/17:00097556
Result on the web
<a href="http://dx.doi.org/10.1016/j.cardfail.2017.04.002" target="_blank" >http://dx.doi.org/10.1016/j.cardfail.2017.04.002</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.cardfail.2017.04.002" target="_blank" >10.1016/j.cardfail.2017.04.002</a>
Alternative languages
Result language
angličtina
Original language name
Prevalence and Predictors of Early Heart Failure with Preserved Ejection Fraction in Patients with Paroxysmal Atrial Fibrillation
Original language description
Patients with atrial fibrillation (AF) have an increased risk of diastolic dysfunction and heart failure. The purpose of this study was to identify independent predictors of early (i.e., only exercise-induced) heart failure with preserved ejection fraction (HFpEF) and to describe the prevalence of early HFpEF among the patients with paroxysmal AF. METHODS AND RESULTS: One hundred patients with paroxysmal AF and preserved left ventricular ejection fraction (LVEF) underwent catheterization with left atrial pressure (LAP) measurements at rest and at the peak of arm exercise (LAP-exe). Based on resting and exercise LAP values, the patients were divided into three groups. Sixty-one patients had no evidence of HFpEF (LAP at rest LESS-THAN OR EQUAL TO15 mmHg, LAP-exe <25 mmHg). Twenty-five subjects had early HFpEF (LAP at rest LESS-THAN OR EQUAL TO15 mmHg, LAP-exe GREATER-THAN OR EQUAL TO25 mmHg, prevalence 25%). Fourteen patients already had HFpEF at rest (LAP >15 mmHg at rest). Multivariate exact logistic regression analysis identified age GREATER-THAN OR EQUAL TO58 years, LAP at rest GREATER-THAN OR EQUAL TO11 mmHg, and peak systolic mitral annular velocity LESS-THAN OR EQUAL TO9.3 cm/s to be independent predictors of early HFpEF. CONCLUSIONS: In patients with paroxysmal AF and preserved LVEF, there appears to be a clinically significant prevalence of early HFpEF.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30201 - Cardiac and Cardiovascular systems
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Cardiac Failure
ISSN
1071-9164
e-ISSN
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Volume of the periodical
23
Issue of the periodical within the volume
7
Country of publishing house
US - UNITED STATES
Number of pages
5
Pages from-to
558-562
UT code for WoS article
000406733500009
EID of the result in the Scopus database
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