First report of Sneathia sanguinegens together with Mycoplasma hominis in postpartum prosthetic valve infective endocarditis: a case report

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F17%3A00067354" target="_blank" >RIV/00159816:_____/17:00067354 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14740/17:00095651 RIV/00209775:_____/17:N0000014

Result on the web

<a href="https://bmcinfectdis.biomedcentral.com/track/pdf/10.1186/s12879-017-2654-8?site=bmcinfectdis.biomedcentral.com" target="_blank" >https://bmcinfectdis.biomedcentral.com/track/pdf/10.1186/s12879-017-2654-8?site=bmcinfectdis.biomedcentral.com</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1186/s12879-017-2654-8" target="_blank" >10.1186/s12879-017-2654-8</a>

Result language

angličtina

Original language name

First report of Sneathia sanguinegens together with Mycoplasma hominis in postpartum prosthetic valve infective endocarditis: a case report

Original language description

Background: The presence of more than one bacterial agent is relatively rare in infective endocarditis, although more common in prosthetic cases. Molecular diagnosis from a removed heart tissue is considered a quick and effective way to diagnose fastidious or intracellular agents. Case presentation: Here we describe the case of postpartum polymicrobial prosthetic valve endocarditis in a young woman. Sneathia sanguinegens and Mycoplasma hominis were simultaneously detected from the heart valve sample using broad range 16S rRNA polymerase chain reaction (PCR) followed by sequencing while culture remained negative. Results were confirmed by independent PCR combined with denaturing gradient gel electrophoresis. Before the final agent identification, the highly non-compliant patient left from the hospital against medical advice on empirical intravenous treatment with aminopenicillins, clavulanate and gentamicin switched to oral amoxycillin and clavulanate. Four months after surgery, no signs of inflammation were present despite new regurgitation and valve leaflet flail was detected. However, after another 5 months the patient died from sepsis and recurrent infective endocarditis of unclarified etiology. Conclusions: Mycoplasma hominis is a rare causative agent of infective endocarditis. To the best of our knowledge, presented case is the first report of Sneathia sanguinegens detected in this condition. Molecular techniques were shown to be useful even in polymicrobial infective endocarditis samples.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30302 - Epidemiology

Project

<a href="/en/project/NV16-31593A" target="_blank" >NV16-31593A: Polymicrobial biofilm - the complex microbiome - in relation to the treatment of nosocomial infections</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

BMC Infectious disease [online]

ISSN

1471-2334

e-ISSN

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Volume of the periodical

17

Issue of the periodical within the volume

AUG 14

Country of publishing house

GB - UNITED KINGDOM

Number of pages

7

Pages from-to

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UT code for WoS article

000407590900002

EID of the result in the Scopus database

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