Molecular diagnosis of culture negative infective endocarditis: clinical validation in a group of surgically treated patients

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00209775%3A_____%2F03%3A%230000254" target="_blank" >RIV/00209775:_____/03:#0000254 - isvavai.cz</a>

Result on the web

<a href="http://heart.bmj.com/content/89/3/263.full.pdf+html" target="_blank" >http://heart.bmj.com/content/89/3/263.full.pdf+html</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Molecular diagnosis of culture negative infective endocarditis: clinical validation in a group of surgically treated patients

Original language description

To assess the clinical validity of polymerase chain reaction (PCR) based molecular methods in the microbiological diagnosis of culture negative infective endocarditis in a group of surgically treated patients. Retrospective case-control study. Referencecardiovascular surgical centre. 15 culture negative patients with infective endocarditis classified according to Duke criteria, with 17 heart valve samples; 13 age and sex matched control patients without infective endocarditis, with 13 valve samples. Medical records were reviewed and clinical, demographic, and microbiological data collected, including results of molecular detection of bacteria and fungi from valve samples. The clinical validity of molecular diagnosis was assessed, along with the sensitivity and speed of the systems. In the study group, 14 patients were PCR positive (93%). Organisms detected were streptococci (3), staphylococci (2), enterobacter (1), Tropheryma whippelii (1), Borrelia burgdorferi (1), Candida albicans (

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EE - Microbiology, virology

OECD FORD branch

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Project

<a href="/en/project/NM6870" target="_blank" >NM6870: Detection of origin of infection after extensive surgical treatment</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2003

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Heart

ISSN

1355-6037

e-ISSN

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Volume of the periodical

89

Issue of the periodical within the volume

3

Country of publishing house

GB - UNITED KINGDOM

Number of pages

6

Pages from-to

263-268

UT code for WoS article

000181276000013

EID of the result in the Scopus database

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