Feasibility of directional percutaneous epicardial ablation with a partially insulated catheter

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F18%3A00069255" target="_blank" >RIV/00159816:_____/18:00069255 - isvavai.cz</a>

Alternative codes found

RIV/62157124:16170/18:43878392

Result on the web

<a href="http://dx.doi.org/10.1007/s10840-018-0404-5" target="_blank" >http://dx.doi.org/10.1007/s10840-018-0404-5</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s10840-018-0404-5" target="_blank" >10.1007/s10840-018-0404-5</a>

Result language

angličtina

Original language name

Feasibility of directional percutaneous epicardial ablation with a partially insulated catheter

Original language description

PurposeTo demonstrate the feasibility of directional percutaneous epicardial ablation using a partially insulated catheter.MethodsPartially insulated catheter prototypes were tested in 12 (6 canine, 6 porcine) animal studies in two centers. Prototypes had interspersed windows to enable visualization of epicardial structures with ultrasound. Epicardial unipolar ablation and ablation between two electrodes was performed according to protocol (5-60W power, 0-60mls/min irrigation, 78s mean duration).ResultsOf 96 epicardial ablation attempts, unipolar ablation was delivered in 53.1%. Electrogram evidence of ablation, when analyzable, occurred in 75 of 79 (94.9%) therapies. Paired pre/post-ablation pacing threshold (N=74) showed significant increase in pacing threshold post-ablation (0.9 to 2.6mA, P&lt;.0001). Arrhythmias occurred in 18 (18.8%) therapies (11 ventricular fibrillation, 7 ventricular tachycardia), mainly in pigs (72.2%). Coronary artery visualization was variably successful. No phrenic nerve injury was noted during or after ablation. Furthermore, there were minimal pericardial changes with ablation.ConclusionsEpicardial ablation using a partially insulated catheter to confer epicardial directionality and protect the phrenic nerve seems feasible. Iterations with ultrasound windows may enable real-time epicardial surface visualization thus identifying coronary arteries at ablation sites. Further improvements, however, are necessary.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30201 - Cardiac and Cardiovascular systems

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing

ISSN

1383-875X

e-ISSN

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Volume of the periodical

53

Issue of the periodical within the volume

1

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

9

Pages from-to

105-113

UT code for WoS article

000444566500013

EID of the result in the Scopus database

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