Percutaneous Epicardial Pacing Using a Novel Insulated Multi-Electrode Lead

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F15%3A00085403" target="_blank" >RIV/00216224:14110/15:00085403 - isvavai.cz</a>

Alternative codes found

RIV/00159816:_____/15:00063409

Result on the web

<a href="http://dx.doi.org/10.1016/j.jacep.2015.04.012" target="_blank" >http://dx.doi.org/10.1016/j.jacep.2015.04.012</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jacep.2015.04.012" target="_blank" >10.1016/j.jacep.2015.04.012</a>

Result language

angličtina

Original language name

Percutaneous Epicardial Pacing Using a Novel Insulated Multi-Electrode Lead

Original language description

Objectives This study hypothesized that shielded electrodes could capture myocardium without extracardiac stimulation. Background Epicardial cardiac resynchronization therapy (CRT) permits unrestricted electrode positioning. However, this therapy requires surgical placement of device leads and risks unwanted phrenic nerve stimulation. Methods In 6 dog and 5 swine experiments, we used a percutaneous approach to access the epicardial surface of the heart and deployed novel leads housing multiple electrodes with selective insulation. Bipolar pacing thresholds at pre-specified sites were tested to compare electrode threshold data, facing both toward and away from the epicardial surface. Results In 151 paired electrode recordings (70 in 6 dogs; 81 in 5 swine), thresholds facing myocardium were lower than those facing away (median threshold of 0.9 [interquartile range (IQR): 0.4 to 1.6] mA vs. 4.6 [IQR: 2.1 to &gt;10.0] mA, respectively, for dogs, p &lt; 0.0001; and 0.5 [IQR: 0.2 to 1.0] mA

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FS - Medical facilities, apparatus and equipment

OECD FORD branch

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Project

<a href="/en/project/ED1.100%2F02%2F0123" target="_blank" >ED1.100/02/0123: St. Anne´s University Hospital Brno - International Clinical Research Center (FNUSA-ICRC)</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

JACC: Clinical Electrophysiology

ISSN

2405-500X

e-ISSN

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Volume of the periodical

1

Issue of the periodical within the volume

4

Country of publishing house

US - UNITED STATES

Number of pages

11

Pages from-to

273-283

UT code for WoS article

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EID of the result in the Scopus database

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